Pavel Moudrý (@3reak) 's Twitter Profile
Pavel Moudrý

@3reak

Group leader at @IMTM_Olomouc @UPOlomouc.
My group explores DNA replication dynamics in response to PARP inhibitors.
@3reak.bsky.social

ID: 2803524823

calendar_today11-09-2014 10:53:14

84 Tweet

122 Followers

335 Following

Hana Sedlackova (@hanasedlackova1) 's Twitter Profile Photo

📢 Happy to share our bioRxiv preprint on how CRL4-DCAF12 regulates the cellular level of MCMBP, a chaperone of nascent MCM2-7 complexes, to ensure error-free genome duplication. The full story can be found here: lnkd.in/eCjVNQks

📢 Happy to share our bioRxiv preprint on how CRL4-DCAF12 regulates the cellular level of MCMBP, a chaperone of nascent MCM2-7 complexes, to ensure error-free genome duplication. The full story can be found here: lnkd.in/eCjVNQks
Tomas Cupr (@tomcuprcz) 's Twitter Profile Photo

Me ve 20s ani nenapadlo picovat co mi mohl kdo dat. Byl jsem trochu lempl. Linej. Tata me “vydedil”, kdyz jsem si za studentsky kontokorent koupil vypalovacku. Studovat se mi nechtelo, sebral jsem se, odcestoval do Anglie, bylo mi 23. Makal jsem manualne, sbiral dvoupencovky na

Institute of Molecular Genetics (@imgprague) 's Twitter Profile Photo

✨Wondering how it looks at IMG? Come and find out! Learn more about our PhD projects 👉img.cas.cz/phd Join us, we are waiting for you! Your future starts now! #phd #phdstudent #science #openpositions #phdcommunity #prague youtube.com/watch?v=FucH5p…

Pavel Moudrý (@3reak) 's Twitter Profile Photo

Looking for a PhD in cutting - edge cancer research? Join DNA replication dynamics group at Institute of Molecular and Translational Medicine NÚVR @UPOL to study PARP inhibitors - key cancer drugs - and their impact on DNA replication. The fight against cancer starts in the lab! #PhDposition #CancerResearch

Looking for a PhD in cutting - edge cancer research? 
Join DNA replication dynamics group at <a href="/IMTM_Olomouc/">Institute of Molecular and Translational Medicine</a> <a href="/NUVR_CZ/">NÚVR</a>  @UPOL to study PARP inhibitors - key cancer drugs - and their impact on DNA replication. 
The fight against cancer starts in the lab! #PhDposition #CancerResearch
Tomas Kapler #AI 🤖✨ (@tkapler) 's Twitter Profile Photo

Co myslíte, koupí si ještě někdo ve světě nějaké americké zbrane ci jiné technologie, když bude vědět, že stačí nepodlehnout vydírání, nenechat se zabíjet Ruskem, nebo si nevzít oblek a amík vám to zařízne? IMO by měly evropské země přehodnotit veškeré vojenské kontrakty a

James Dewar (@jamesmdewar) 's Twitter Profile Photo

🧬⛓️‍ Our latest preprint examines the fate of collapsed forks in vertebrates 🐸 and our colleagues in @heathmurraylab asked similar questions in bacteria 🦠 Together our studies indicate that the response to fork collapse is shaped by evolution (see🧵) biorxiv.org/content/10.110…

Alex Hormozi (@alexhormozi) 's Twitter Profile Photo

People demand success but refuse to work weekends. People want opportunity but won't talk to strangers. People claim ambition but sleep in everyday. We are the result of our actions not our aspirations.

nature (@nature) 's Twitter Profile Photo

Nature research paper: BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filaments go.nature.com/3RlDBNB

Hana Sedlackova (@hanasedlackova1) 's Twitter Profile Photo

📢 For all DNA fiber enthusiasts! 🟥🟩 We are thrilled to announce the release of our long-awaited AI-based workflow for the automated and quantitative analysis of DNA fibers. It's an exciting step forward—check it out on bioRxiv! lnkd.in/dQWUPtsP

📢 For all DNA fiber enthusiasts! 🟥🟩 We are thrilled to announce the release of our long-awaited AI-based workflow for the automated and quantitative analysis of DNA fibers. It's an exciting step forward—check it out on bioRxiv! lnkd.in/dQWUPtsP
Pavel Moudrý (@3reak) 's Twitter Profile Photo

Our new preprint is now on bioRxiv! 📄 We introduce qAID, an AI-based workflow for automated analysis of DNA replication dynamics. Glad to have contributed a small part to this study.

Pavel Moudrý (@3reak) 's Twitter Profile Photo

🧬 Zbývá už jen poslední měsíc na přihlášení na PhD pozici zaměřenou na výzkum replikace DNA. Přidej se k našemu týmu a podílej se na špičkovém biomedicínském výzkumu! 📍Ústav Molekulární a Translační Medicíny, UPOL Olomouc 📅 Deadline: 15.5.2025 researchjobs.cz/job/phd-pozice…

J Cell Science (@j_cell_sci) 's Twitter Profile Photo

Cell scientist to watch – Hana Polasek-Sedlackova Hana Sedlackova In this interview, we learn about Hana’s career, her insights on collaborative research and her engineering hobby. journals.biologists.com/jcs/article/13…

Cell scientist to watch – Hana Polasek-Sedlackova <a href="/HanaSedlackova1/">Hana Sedlackova</a>

In this interview, we learn about Hana’s career, her insights on collaborative research and her engineering hobby.
journals.biologists.com/jcs/article/13…
altmeyerlab (@altmeyerlab) 's Twitter Profile Photo

Sharing our latest work University of Zurich tracking DNA damage inheritance by Live+QIBC nature.com/articles/s4158…. Huge congrats to Andreas Panagopoulos, M. Stout and all co-authors for this tour de force! Beautifully summarized by Sarah Aitken and E. Reilly Nature News & Views nature.com/articles/d4158….

Molecular Cell (@molecularcell) 's Twitter Profile Photo

Online Now: The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks dlvr.it/TLZkmH

Online Now: The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks dlvr.it/TLZkmH
Molecular Cell (@molecularcell) 's Twitter Profile Photo

Online Now: The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells dlvr.it/TLZtS1

Online Now: The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells dlvr.it/TLZtS1
Marián Hajdúch (@marian_hajduch) 's Twitter Profile Photo

CO JE HLAVNÍ PŘÍČINOU EPIDEMIE OBEZITY? MÁLO HÝBEME, NEBO SE PŘEJÍDÁME? 🔬 Studie publikovaná v časopise PNAS ze 34 populací napříč světem – od lovců-sběračů až po moderní města – ukazuje, co skutečně stojí za epidemií obezity. A není to lenost. 👣 Výzkumníci sledovali přes 4

CO JE HLAVNÍ  PŘÍČINOU EPIDEMIE OBEZITY? MÁLO HÝBEME, NEBO SE PŘEJÍDÁME? 

🔬 Studie publikovaná v časopise PNAS ze 34 populací napříč světem – od lovců-sběračů až po moderní města – ukazuje, co skutečně stojí za epidemií obezity. A není to lenost.

👣 Výzkumníci sledovali přes 4
Journal of Cell Biology (@jcellbiol) 's Twitter Profile Photo

.Anoop Kumar Yadav, Jadhav, Jakub Svenda, Hana Sedlackova et al. present a novel cell-permeable biotin-HaloTag ligand. The reported ligand enables in vivo labeling & provides capabilities for efficient affinity capture of protein variants from live cells. hubs.la/Q03xv9Sd0

.<a href="/yadav_anoop101/">Anoop Kumar Yadav</a>, Jadhav, <a href="/SvendaJakub/">Jakub Svenda</a>, <a href="/HanaSedlackova1/">Hana Sedlackova</a> et al. present a novel cell-permeable biotin-HaloTag ligand. The reported ligand enables in vivo labeling &amp; provides capabilities for efficient affinity capture of protein variants from live cells. hubs.la/Q03xv9Sd0