AI tools are showing potential to augment the development of children with Down syndrome. A letter to the editor outlines several ways ChatGPT could act as a learning companion and conversational partner – from delivering tailored educational content to helping build social

We still don’t fully understand how the skull deforms in a head-first impact, and that limits how well we can model spinal injuries. To address this, scientists tested 22 human heads under controlled vertical impacts at speeds of 1, 2, and 3 m/s, with the skulls supported at the

What makes lab-grown tissues or bacterial cultures thrive – or fail – under engineered conditions? A new study takes aim at a key limitation in tissue engineering and microbiome research: understanding how fluid-induced shear stress affects cells and microbial communities. The

While citation metrics are just one lens through which to measure an academic journal's quality, they can offer a meaningful signal of a publication’s influence in the field. We’re grateful to share that Annals of Biomedical Engineering (ABME) has received an increase in its

Millions of people rely on continuous positive airway pressure (CPAP) machines to treat sleep apnea, but those using one-size-fits-all masks often experience discomfort and air leaks. To improve mask fit, engineers developed a device that measures how soft and elastic facial

Choosing the right artificial heart valve can be a matter of life and death, but doctors don’t always have clear data to guide the decision. To address this gap, researchers used a high-resolution Tomo-PIV imaging system to analyze the flow dynamics of three valve types under a

Heart failure with preserved ejection fraction (HFpEF) presents a major clinical challenge, especially because many patients cannot benefit from standard mechanical support devices due to structural differences in the heart. Researchers investigated a new way to help HFpEF

Efforts to prevent head injuries in sports increasingly depend on instrumented mouthguards (iMGs), making it essential to understand how well these devices capture real impacts. Toward this need, engineers tested two iMGs – one from Prevent Biometrics and one from Diversified

High blood pressure is a known risk factor for heart disease, but what happens when it interacts with artificial heart valves? Researchers used a heart simulator and particle image velocimetry to explore how different blood pressure conditions affect coronary blood flow after

Getting nanoparticles “just right” remains a major obstacle to progress in drug delivery, diagnostics, and materials science. To address this, researchers developed a computational fluid dynamics (CFD) pipeline to reduce the trial-and-error typically required to formulate

Why are more young people experiencing diseases once considered exclusive to aging? In a review, researchers examine advanced glycation end products (AGEs) – molecules that form when proteins or fats combine with sugars – as central players in aging and chronic disease. The

Concerns about citation practices that may undermine academic integrity are drawing increasing attention. A letter to the editor confronts the issue of researchers entering into reciprocal citation partnerships, agreements in which authors cite each other’s work to inflate

Modeling how human cells move through the body’s narrowest channels could unlock faster, more scalable insights into health and disease. To support that work, researchers have developed a new coarse-grained model to simulate the flow mechanics of eukaryotic cells – accounting

Most drug candidates never make it to market, and one major reason is that we still struggle to predict how they’ll affect the human liver. In a review of experimental liver models, researchers trace the evolution from traditional 2D cultures to 3D systems and liver-on-a-chip

Measuring the strain on your knees shouldn’t require a lab coat and a high-tech lab. Researchers are working to democratize the science of joint health by replacing traditional motion capture analysis with more accessible tools. Using artificial neural networks trained on basic

Rebuilding damaged bone tissue is a long-standing challenge in medicine, and current manufacturing techniques often fall short in precision, consistency, or scalability. A new study presents a novel method for producing bone scaffolds made of poly(DL-lactide-co-glycolide) and

Which surgical technique keeps blood flowing safer after mitral valve repair? Researchers used computational fluid dynamics, powered by cine-MRI data, to compare two common surgical approaches for mitral valve prolapse: Neochordae and Resection. By simulating both techniques in

The cells that keep our cartilage intact rely on energy, but how they generate and use it is still being uncovered. Scientists measured whether human chondrocytes – cells responsible for repairing cartilage – produce measurable heat while metabolizing nutrients like glucose and

Many patients with artery-narrowing diseases undergo procedures that fail to deliver medications evenly, putting long-term treatment outcomes at risk. Exploring the root of this issue, researchers used computational simulations to examine how balloon catheter design affects

Many people with cerebral aneurysms undergo treatment with a device called a flow diverting stent (FDS), but in some cases, the aneurysm doesn't fully heal – and no one knows why. Probing this mystery, researchers used 3D-printed, patient-specific aneurysm models and applied