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New this week in Arthritis Care & Research 🛏️💤 Sleep parameters and self-reported fatigue in patients with rheumatoid arthritis doi.org/10.1002/acr.25… 📋⚪ Claims-based algorithms to evaluate ongoing prednisone use in patients with rheumatoid arthritis doi.org/10.1002/acr.25…

New strategies are needed for effective non-surgical treatments for osteoarthritis. Commentary in A&R reviews two potential non-surgical treatments, gait modification using special shoes equipped with rubber balls and the beneficial impact of weight loss doi.org/10.1002/art.43…

A 61-year-old man with history of chronic eosinophilic rhinosinusitis and eosinophilic asthma managed with benralizumab presented with sudden bilateral visual loss and transient amaurosis Case report in ACR Open Rheumatology doi.org/10.1002/acr2.7…

Among >40k rheumatoid arthritis patients in the Korean NHID database, patients with newly diagnosed RA did not have increased risk of thyroid cancer compared to non-RA population. Thyroid cancer incidence was not affected by serologic status AC&R doi.org/10.1002/acr.25…

Can clinical labs distinguish between disease flare and infection in SLE patients with fever? EHR study found that ESR:CRP ratio + C3 & C4 levels and WBC, neutrophil, & monocyte counts could discriminate lupus flare from culture pos or neg infection ACROR acrjournals.onlinelibrary.wiley.com/doi/10.1002/ac…

Do NSAIDs lead to underestimation of active sacroiliitis on MRI? Among >300 axSpA patients in the UK receiving NSAIDs, 1/5 showed full resolution of active sacroiliitis lesions. Finding suggest consideration of NSAID washout prior to MRI AC&R doi.org/10.1002/acr.25…

Exploring the relationship between air quality and rheumatoid arthritis disease activity in Kuwait revealed associations between DAS28 scores and pollutants. In particular, NO₂ and O₃ were strong predictors of increased disease activity AC&R doi.org/10.1002/acr.25…

Phase II/III trial assessed ivarmacitinib (JAK1 inhibitor) for active ankylosing spondylitis. Ivarmacitinib 4 mg showed improved ASAS20 response at wk 12 vs placebo, with efficacy sustained through 24 wks. Infection-related AEs were similar b/w groups A&R doi.org/10.1002/art.43…

Muscle biopsies were examined to define phenotypes & features of muscle vasculitis. Patients w/ muscle vasculitis often had normal CK levels, and less weakness compared to IIM. Muscle vasculitis histology often lacked myofiber necrosis/infiltration ACROR doi.org/10.1002/acr2.7…

Mouse model explored how TRIM21 regulates local & sys. inflammation from UVB exposure. Loss of Trim21 was assoc. with ↑sensitivity to UVB, resulting in splenomegaly & induction of type I IFNs, reinforcing TRIM21 as neg. regulator of IFN-I response A&R doi.org/10.1002/art.43…

Open-label trial assessed rapid escalation to golimumab (TNFi) in early axSpA gut inflammation. 73% of patients required escalation, of whom 55% achieved sustained remission. 78% of patients who discontinued treatment had disease relapse within 1 year A&R doi.org/10.1002/art.43…

👓📄 Read the latest studies this week in Arthritis & Rheumatology RCT of abatacept for relapsing, non-severe GPA doi.org/10.1002/art.43… Long-term exposure to PM2.5 and risk of SARDs doi.org/10.1002/art.43… Phase II/III trial of ivarmacitinib for ankylosing spondylitis

✨ New this week in Arthritis Care & Research No increased risk of thyroid cancer in patients with newly diagnosed RA doi.org/10.1002/acr.25… NSAID use may lead to underestimation of active sacroiliitis on MRI doi.org/10.1002/acr.25… Relationship between air quality and

New this week in ACR Open Rheumatology 📖 Using clinical labs to distinguish between disease flare and infection in SLE patients with fever doi.org/10.1002/acr2.7… 📖 Examining muscle biopsies to define phenotypes and features of muscle vasculitis doi.org/10.1002/acr2.7…