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Penumbra’s interventional clot removal platform—including CAT RX™ and Lightning Flash™ 2.0 with Element—offers innovative solutions for coronary thrombus management and Pulmonary Embolism. #Sponsored by Penumbra, Inc. | Learn more here: citoday.com/articles/2025-…

n this prespecified analysis of a randomized clinical trial, patients with HFimpEF remained at high risk of CV events, underscoring the need for continued management despite LVEF improvement. jamanetwork.com/journals/jamac…

Chronic stent recoil occurred in 1 of 5 lesions treated with second- or newer-generation #DES requiring repeat #revasc, with severe calcium and nonuniform stent expansion identified as risk factors, and was associated with TLR. jacc.org/doi/10.1016/j.… #JACCINT #OCT

Compared with Lp(a) ≤30 mg/dL, individuals with Lp(a) >30 to ∼50 mg/dL exhibited 11%, 15%, 9%, and 11% greater odds of increased carotid intima-media thickness, carotid plaque, subclinical brain infarcts, and coronary artery calcification, respectively. jacc.org/doi/10.1016/j.…

In stable patients with extensive noncalcified plaque volume at baseline, 18 months of evolocumab treatment was associated with a shift toward a lower risk quantitative plaque phenotype and reduction in microcalcification activity jacc.org/doi/10.1016/j.…

Among older adults with high-risk or intermediate-risk PE, patients treated with CBT experienced lower mortality over the follow-up of up to 3 years, but higher risk of in-hospital bleeding complications. jacc.org/doi/10.1016/j.…

Annual observed cardiac mortality exceeded expected from 2020 to 2023: 16% (95% CI, 13%-19%) higher in 2020, 17% (95% CI, 14%-21%) higher in 2021, 17% (95% CI, 13%-21%) higher in 2022, and 6% (95% CI, 2%-11%) higher in 2023 jamanetwork.com/journals/jaman…

ATTR-specific treatment and AVR both result in significant survival benefit in dual pathology AS and ATTR-CA. Results should be interpreted in the context of the non-randomized study setting and differences in patient characteristics. academic.oup.com/eurheartj/adva…

High PCATRCA was independently associated with PoCE after PCI using current-generation DES. Combining PCATRCA with traditional cardiovascular risk factors and cCTA findings may enhance risk assessment for PoCE after PCI. eurointervention.pcronline.com/article/impact…

Among persons with both chronic kidney disease and type 2 diabetes, initial therapy with finerenone plus empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either treatment alone. nejm.org/doi/full/10.10…

Carvedilol as Single Therapy for Heart Failure With Improved Ejection Fraction: A Randomized Clinical Trial (CATHEDRAL-HF) | JACC: Heart Failure jacc.org/doi/10.1016/j.…

Results of this cohort study suggest that the prevalence of CMP-PLP variants was substantial in patients with early-onset AF. Patients with AF carrying a CMP-PLP variant had an increased risk of future CMP/HF, independent of clinical and polygenic score jamanetwork.com/journals/jamac…

📊 In >40,000 #PCI patients, skipping antiplatelet meds doubled the risk of death, MI, or arrest 💔 🕒 Risk was consistent across 3 yrs post-PCI 💊 Lifelong adherence isn't just recommended—it’s critical jacc.org/doi/10.1016/j.… Yuichiro Mori, MD, MPH #JACCAsia #cvMI #DES #AdherenceMatters

Aortic valve calcification scoring on contrast CT have high AUCs to identify severe AS by echo; optimal thresholds >1840 for men and >1430 for women Tom Wang MBChB MD Tiffany Dong Elio Haroun Cleveland Clinic Heart, Vascular & Thoracic #AHAJournals Kaz Negishi@Cardiologist/ Heart Mafia ahajrnls.org/409MAGy

The findings reveal positive associations between cannabis use and MACE. These findings should encourage investigating cannabis use in all patients presenting with serious cardiovascular disorders. heart.bmj.com/content/early/…

Immune checkpoint inhibitors and increased risk for atherosclerosis

No association between preprocedural fasting and witnessed pulmonary aspiration: A systematic review and meta-analysis - ScienceDirect sciencedirect.com/science/articl…

These findings enhance mechanistic insights into the effect of valsartan in early-stage HCM jamanetwork.com/journals/jamac…

Results of the FINEARTS-HF randomized clinical trial demonstrate that the PREDICT-HFpEF models performed well in terms of calibration and discrimination. Baseline risk did not modify the benefit of finerenone. jamanetwork.com/journals/jamac…

this study, an AI system that automatically interprets echocardiograms maintained high accuracy across geography and time from complete and limited studies. This AI system may be used as an adjunct reader in echocardiography laboratories jamanetwork.com/journals/jama/…