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You can leverage imperfect chemosensors with cross-reactivity or off-range LOD for better results, especially in complex biological samples. Here is our short introductory concept paper on ChemEurJ: Chemistry - A European Journal dx.doi.org/10.1002/chem.2… KOREA UNIVERSITY MEDICINE(고려대학교의료원)

Imogen’s work investigating a transient Al(I) species is now available online as an accepted article in Chemical Communications - supported by Mickey and some serendipitous crystal growing by Juliana. Congratulations Imogen S 💥 pubs.rsc.org/en/content/art…

Chemo-click: our latest strategy to image subsets of cells. Rapid and modular approach, in principle suitable for many #chemokines and #immune cells. Terrific work by Marco Bertolini, Lorena and utsa karmakar, just published Journal of the American College of Surgeons (JACS). Free link: pubs.acs.org/doi/10.1021/ja…

👉Imaging Tools for Chemical Biology Edited by Lei Feng and Tony James (Tony James) 🔗bit.ly/4hvOUyU 🔍This book provides a comprehensive overview of multimodal and combined techniques used for imaging applications in Chemical Biology.

Fluorescent Chemosensors in the Creation of a Commercially Available Continuous Glucose Monitor | ACS Sensors pubs.acs.org/doi/10.1021/ac…

“Structure-Activity Optimization of Phenoxy-1,2-Dioxetane Precursors as Probes for Singlet Oxygen Yields Unprecedented Detection Sensitivity”, Appearing now in ChemRxiv: chemrxiv.org/engage/chemrxi…

Anyone working on NRF2 activation in cancer? If so, this might be of interest to you. nature.com/articles/s4146…

The OG Samarium Benzene Tetra-Anion (rdcu.be/d5pQi) out now in Nature Chemistry. Big thanks to everyone who worked on this, too many to name all of them here. Just wanted to say a special thank you to Georgia Richardson on this work, great way to finish your PhD!

Check out Jennifer Hiscock excellent preview of @philgale/Gale Research Group ’s back to back Chem papers developing the next generation of synthetic anion carriers. It also includes a fantastic summary of the organelle selective transporters I developed during my PhD!

The Goldup Lab PhD projects available in range of areas - something for everyone! Join us to do cool chemistry using the mechanical bond in catenanes & rotaxanes for real world applications in the shiny shiny new Molecular Sciences Building UoBChemistry 😊 Reposts appreciated!

Congrats to all involved in this excellent collaboration, led by Xingzao (Yujia Qing and Hagan Bayley group) Aidan K Oxford Chemistry #nanopore #photoswitch #ion transport

I am thrilled that our work on MemGraft probes for “permanent” fluorescent labelling of plasma membranes is out in JACS Au! We established a concept of lipid-directed covalent labeling of plasma membranes. Open access: pubs.acs.org/doi/10.1021/ja… MemGraft probes allow cell fixation,

Pleased to share some of our collaborative work between Enamine Ltd 🇺🇦 and Pfizer Inc. on the development of new saturated heterocycle building blocks for use in medicinal chemistry!

Excited to share this collaborative paper out in ChemPhotoChem with Donal O'Shea (RCSI_Chemistry) and Michael Hall looking at inherently chiral heterocycles made via strain promoted click reactions. Newcastle Chemistry Sciences at Newcastle Read it here: …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cp…

Fantastic talk by Adam C. Sedgwick King's College London in our TCD School of Chemistry seminar programme on the development of range of Pd-based luminescent prodrugs for cancer. What a fantastic way to close our 2024-5 Seminar Series

4-year PhD studentship now available at King's College London with Adam Sedgwick and myself on making small molecule pro-drugs that can be activated by different types of radiation, including radioactivity. More info here: findaphd.com/phds/project/s…

Ever wondered about the chemistry behind the oddly named medical condition called “popcorn lung” ? RCSI-Chem Prof O’Shea explains all in The Conversation (theconversation.com/uk) article out today…..theconversation.com/popcorn-lung-h… Research Ireland and ICI Ireland

Our first photoswitchable channel, controlled by three separate stimuli, up now@ChemRxiv! tinyurl.com/3m4umy3d - we use F-azobenzenes and a pillar[5]arene core to control ion transport + light, pH, and guest, modulating initial rates 170-fold. Collaboration + Mark Wallace!

Check out our recent work J. Am. Chem. Soc. on cancer immunotherapy with a gold drug. Built on our previous work, we now showed that a new water-soluble Au-NHC can induce a year-long (!) immune memory response against colon cancer cells via immunogenic cell death. pubs.acs.org/doi/full/10.10…

📣Preprint 📣 You want to degrade a protein in Gram-negatives? We have tackled this challenge! Detailed study of our Light-Activated Metal-Dependent Protein Degradation LAMP-D system in targeting and rescuing NDM-1 activity. What an amazing team effort 🫶🏻 doi.org/10.26434/chemr…