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In this study, the authors take a panoramic look at how polygenic risk score (PRS) performance for major common diseases has evolved over the past 15 years. While GWAS sample sizes have steadily grown year after year, the gains in PRS accuracy showed strong early momentum but

Absolutely crazy month for progress in the world of genome instability & DNA repair, especially as pertaining to aging. A few of the most exciting papers, a 🧵: