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Join Dr. Ashley Odai-Afotey (Ashley Odai-Afotey, MD) at the #ASCO25 Care Delivery/Models of Care poster session on Sunday and learn how race and ethnicity impacted intervention adherence, engagement, and tool utilization in the #BreastCancer weight loss (#BWEL) trial (Alliance for Clinical Trials in Oncology

We enrolled #PDIGREE over 5 yrs including a pandemic, and in that time, 7 phase 3 trials read out that shaped the metastatic #kidneycancer landscape. Grateful for support throughout Alliance for Clinical Trials in Oncology National Cancer Institute to complete this smart/fortunate trial design. #ASCO25 OncoAlert 6/n

After many years of hard work starting in 2014, we present Step 1 of #PDIGREE presented by Tian Zhang, MD, MHS in advanced RCC ! 1100 patients and 400+ sites ! #ASCO25 ASCO Alliance for Clinical Trials in Oncology

Cancer survivorship isn’t just about living — it’s about thriving. On #NationalCancerSurvivorsDay, we #CelebrateLife and honor the strength of survivors everywhere. Let's also champion the power of #cancerresearch to make survivorship not only possible, but fuller. #NCSD2025

Kudos to Frank Sinicrope, MD, the study team, enrolling sites/institutions, clinical research specialists/staff, partners/collaborators & most of all - study participants on the results of A021502/ATOMIC - a study for pts with dMMR colon cancer! Learn more: bit.ly/ATOMIC-ASCO

CTx vs CTx + atezolizumab as adj. therapy for stage III deficient DNA MSI/ dMMR mCRC 🔥#ASCO25 Plenary session🔥 🔎Alliance A021502; ATOMIC 👉mDFS 86.4 vs 76. 6, HR 0.5 👉Benefit in all subgroups, OS not yet mature 👉Manageable safety profile 🧐 Practice changing, new SOC

First up at #ASCO25 Plenary: According to ATOMIC results, adding atezo to FOLFOX improves DFS in stage III dMMR #ColonCancer & yields 50% reduction in the risk of recurrence & death vs chemo alone: brnw.ch/21wT4N9 #ASCODailyNews Frank Sinicrope, MD @mayoclinic Myriam Chalabi

1st Plenary #ASCO25: #ATOMIC Ph III, adj mFOLFOX + Atezolizumab vs. mFOLFOX in Stg III dMMR colon ca. - 3yr DFS 86.4% vs 76.6% (HR 0.50), benefit seen in all subgroups. DFS 100% in Niche2 - ⬆️ discontinuation w/ Atezo - OS not mature - ⬆️ Gr4 neutropenia - To Adj or to NeoAdj?

Congrats to the ATOMIC/A021502 investigators ! Alliance for Clinical Trials in Oncology positive DFS and OS for adjuvant dMMr CRC. Years of work and hundreds of patients. NCICancerTrials ASCO

Hats to Amylou Dueck, PhD on your presentation at #ASCO25 on the patient-reported outcomes results from the Alliance for Clinical Trials in Oncology A021602/CABINET trial.

Kudos to Alliance for Clinical Trials in Oncology Breast Committee Co-Chairs - Jennifer Ligibel, MD and Ann Partridge MD, MPH!

Now Available Metro-MN Community Oncology Research Consortium locations >>> the Alliance for Clinical Trials in Oncology A012301 (LoTam) study to compare the effect of low dose tamoxifen to usual hormonal therapy in treating post-menopausal women w/hormone positive HER2- early-stage bit.ly/Alliance-A0123…… #NCI #NCTN #BCsm

At least 40% of #cancers are linked to things we can change or manage, such as: - Avoiding tobacco - Protecting your skin - Limiting alcohol - Keeping a healthy weight - Getting tested for hepatitis C Learn how to lower your risk: bit.ly/3VbeyQk

Congratulations to UNC Lineberger’s Ethan Basch, MD, MSc, FASCO and the e-PRO initiative on receiving the Clinical Innovation Award from Healio and City of Hope! This honor recognizes groundbreaking work to improve patient care through electronic patient-reported outcomes.

For #TrialTuesday, Ardaman Shergill UChicagoCancerCenter leads #ComboMATCH Treatment Trial A6 to compare chemo w/wo binimetinib to shrink tumors in patients with advanced biliary tract cancers in a 2nd line setting. Learn more: bit.ly/cmatch-A6 #PrecisionMedicine Alliance for Clinical Trials in Oncology

Standard chemo is the norm for metastatic #colorectalcancer — but can more be done? The #ERASur trial is exploring whether adding radiation, heat therapy or surgery can extend life. Learn more: bit.ly/Alliance-A0221… Colon Cancer Coalition Fight Colorectal Cancer @ColorectalCAN #TrialTuesday #NCI

Testing for certain features in cancer (biomarkers) can tell doctors about what’s causing it to grow. The #myeloMATCH study uses advanced biomarker testing for adults with #AML or #MDS. 1-800-4-CANCER or swog.org/myeloMATCH National Cancer Institute Alliance for Clinical Trials in Oncology CCTG ECOG-ACRIN Cancer Research Group

#ICYMI .Thomas Hope UC San Francisco .Sukhmani (Suki) Padda MD Cedars-Sinai lead Alliance for Clinical Trials in Oncology A021901/B-LuRE that studies the effect of everolimus vs 177Lu-dotatate in patients w/bronchial #neuroendocrine tumors. Learn more bit.ly/Alliance-A0219… #bronchialcancer #NCI #NCTN #NETs ECOG-ACRIN Cancer Research Group Fight Colorectal Cancer

#DYK #ERASur led by Eric Miller The James is testing whether adding targeted treatments like surgery, radiation or heat therapy to standard chemo can help people w/metastatic #colorectalcancer live longer: bit.ly/Alliance-A0221… Fight Colorectal Cancer @ColorectalCAN Colon Cancer Coalition

The #ERASur trial is enrolling patients w/#colorectalcancer that has spread beyond the liver. Patients who responded well to initial chemo & have up to 4 treatable cancer sites be eligible to participate. Learn more: bit.ly/Alliance-A0221… Fight Colorectal Cancer Colorectal Cancer Alliance @COLONTOWN