🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

DDA is still great for many applications, and #MSFragger-DDA+ improves peptide identification rates via full isolation window search. Huge boosts in IDs, including Astral DDA! Fully integrated in #FragPipe, simply annotate your DDA files as DDA+ and RUN. nature.com/articles/s4146…

we have greatly improved memory in chatgpt--it can now reference all your past conversations! this is a surprisingly great feature imo, and it points at something we are excited about: ai systems that get to know you over your life, and become extremely useful and personalized.

Excited to share our new paper out in nature revealing cell-type specific nuclear organization and its link to gene regulation using new spatial multi-omics technologies! nature.com/articles/s4158…

🧵How does the genome find its place in the 3D space of the nucleus after fertilization? Out now Cell: cell.com/cell/fulltext/… 👇 A thread 👇

Job alert! We are looking for postdoc interested in quantitative methods to understand metabolic programming in cancer and immune cells! Also recruiting technician to help manage lab instruments and projects. DM or email me or forward to anyone you think that might be interested!

Why test #celltherapies one-by-one when you can use multiplexed #SynBio, #proteinengineering & #ML to design, measure & track them at scale? The Goodman Lab Penn Medicine opens July 2025. We’re hiring Specialists & Postdocs! Apply @ bit.ly/42BnJNJ RTs appreciated!🙏

Pairs of split protein segments can modify a variety of target proteins in a living cell Science Magazine Ophir Shalem Jenna Beyer GB science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…

In the latest issue! Global analysis of protein turnover dynamics in single cells dlvr.it/TKXbBG

Our paper on the impact of protein leakage due to loss of membrane integrity for single cell proteomic sample prep is out in Nature Communications! We analyze thousands of primary single cells from murine tracheal tissue and record membrane permeability🧵 nature.com/articles/s4146…

"Native nucleosomes know where to go!” Our Condense-seq paper is now published in Nature! 📄 nature.com/articles/s4158… I’m deeply grateful to my PhD advisor Taekjip Ha and our incredible collaborators The Muir Lab , Bin Zhang , Erika Pearce, and Ben Garcia lab!!

How did humans grow such large brains? These mice might provide the answers go.nature.com/432nP15

Excited to share our latest paper on liver regeneration! We discovered epigenetic mechanisms regulating the plasticity of hepatocytes revealing therapeutic avenues to generate new bile duct cells in liver diseases. #StemCells #RegenerativeMedicine. cell.com/cell-stem-cell…

Very excited to share our latest work in Molecular Cell showing NPM1 stabilizing the association of nucleolus associated domains (NADs) and recruiting G9a to establish their repressive chromatin states. sciencedirect.com/science/articl…

nature.com/articles/s4158…

🚨Call for Papers! We invite submissions to the upcoming JoVE collection on Mass Spectrometry-Based Approaches in Chromatin Biology, for which I’m serving as Guest Editor. Showcase your MS workflow in a visual, peer-reviewed format. More info 👉 app.jove.com/methods-collec…

New method drop: HCR-Proxy, a modular proximity labelling approach to profile local proteome composition around RNA at nanoscale subcompartmental resolution. We resolved nested nucleolar layers and uncovered the grammar of spatial protein partitioning. shorturl.at/OdUdH

🚨 Looking for postdocs! I'm starting my lab at UT Southwestern this September. If you're interested in: 🧬 Somatic & germline mutagenesis 🐭 Evolution of mutation processes 🧠 Adjacent areas like Mendelian genomics & population genetics. Formal ad coming soon. DM me!

Excited to share our latest manuscript in Cell. Here we discovered neuropeptides that specify and reprogram the division of labor in leafcutter ants! penntoday.upenn.edu/news/what-can-…

WE ARE HIRING: Postdoc Positions! Join us at UPenn in vibrant Philly, cutting-edge science, great city, amazing team. Please share and let's get in touch!

Our preprint describing the Range Extender element, which is required and sufficient for long-range enhancer activation at the Shh locus, is out in nature. nature.com/articles/s4158…