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Beautiful work from Tom McWilliams -lab. An encyclopedia of mitophagy in aging mammalian brain.

Biomedicum Foundation Prize 2024 to Yilin Kang for her nature article of DNA polymerase gamma in antiviral defense & disease. So happy for Yilin Kang &Tuula Manninen Anu Suomalainen-Wartiovaara Lab Olli_Vapalahti team STEMM Research Program. Thank you PolG Foundation, Erkko Foundation EMBO Suomen Akatemia | Research Council of Finland

Lapsen tai nuoren kiinnostuksen kipinän havaitseminen ja sen puhaltaminen liekkiin voi antaa suuntaa koko elämään. Kolumnini: Naapurin miehen kallis perintö. Lääkärilehti Medicine and Health, University of Helsinki University of Helsinki laakarilehti.fi/mielipide/naap…

Moving over to Bsky, but keeping still also X active at least for a while. I use the same handle Anu Suomalainen Wartiovaara.

Metabolome is the closest of all ”omes” to phenotype. It should be a standard readout in research and therapy trials. It will become a key diagnostic test in the future. But sample extraction & analysis vary making data collection to common databanks an issue. Solutions?

Kaksi toivetta #TINille: perustutkimuksen vahvistaminen ja kansallinen tuki yliopistojen tki-rahoitukselle. Valtioneuvosto | Statsrådet Sari Multala Wille Rydman Johanna Moisio University of Helsinki Yliopisto-lehti helsinki.fi/fi/uutiset/yli…

This mito-ambassador starts her trans-atlantic journey to spread the word. In Cambridge, UK, honoured to give the 9th Sir John Walker lecture. Then to Ottawa University. Looking forward to interesting discussions. University of Helsinki Medicine and Health, University of Helsinki STEMM Research Program Anu Suomalainen-Wartiovaara Lab

5 yrs ago I needed a tool to find patients with low blood NAD+. Liliya Euro Anu Suomalainen-Wartiovaara Lab succeeded to develop a scalable, accurate test for main redox regulators from any biological material: NAD+, NADH, NADP+, NADPH, GSH, GSSG from a single sample. This became NADMED.

Congrats to Salma Merchant for Cell Stem Cell paper: effects of fatty acid oxidation in hematopoietic stem cells are context dependent. FAO not necessary in young HSCs, but becomes necessary during aging, & deleterious when upregulated by a high fat diet. cell.com/cell-stem-cell…

Stoked to share TWO preprints on mitochondrial pearling! 🎉 We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024.1…), and Gabriel (Gav) Sturm et al. dissect the biophysics behind it (doi.org/10.1101/2024.1…). Details below! 🔬🧵

Tässä jutussa on annettu ymmärtää että syöty kreatiini vaikuttaisi aivoihin. Näin ei kuitenkaan nykytiedon mukaan tapahdu kuin pikkulapsilla. Aikuisten aivot tuottavat oman kreatiininsa itsenäisenä muusta kehosta, eikä syöty lisä siihen vaikuta. hs.fi/urheilu/art-20…

A triumph of science, a miracle of medicine - built on decades of public investment into the US basic and translational biomedical research ecosystem. Magnificent effort led by Drs Rebecca Ahrens-nicklas (CHOP) and Kiran Musunuru (Penn) + IGI + Danaher. innovativegenomics.org/news/first-pat…

“I am genuinely thrilled about the potential of this project to forge new understanding + enhance metabolic health across tissues.” Anu Suomalainen Wartiovaara + Pekka Katajisto are working together to establish broad principles of metabolism that could inform future research