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Super excited to share that our paper on how specific dietary lipids extend lifespan is out now Nature Cell Biology doi.org/10.1038/s41556…

Congratulations Payel Sen Payel on your exciting new publication! sciencedirect.com/science/articl…

NASH therapies head toward landmark approval nature.com/articles/s4158…

Excited to share the lab's newest preprint led by #BryanTeefy, out today on bioRxiv, showing our efforts to map out important immune and metabolic cell types in cells of female ♀️ and male ♂️ African turquoise killifish 🐟🐟🐟! a 🧶 1/7 biorxiv.org/content/10.110…

Apparently these days journals think it’s ok to reject based on « novelty » after wasting 6 months and inviting a revision. Don’t invite a revision if you don’t think it will meet « novelty » standards 🤦‍♀️🤦‍♀️🤦‍♀️

Congratulations Ana Paredes, Ph.D. on an amazing publication! nature.com/articles/s4158…

Such a pleasure to collaborate with this terrific group! Kaechlab (Sue Kaech) @_Bryan_McD Brent Chick I learned so much and enjoyed the opportunity to share our expertise on SWI/SNF to such an elegant cell fate decision! cell.com/immunity/fullt…

Charles Brenner, PhD Harvard University I agree with you on this one 😬. Using these chemicals for reprogramming is not new (shown multiple times b4). Also, this data does not suggest you can just put them in a pill and rewind human organismal aging. I love the field of reprogramming, but jumping the gun will only hurt

Excited to be part of this. Scientists take note - you can set up your own journal. The big publishers are not indispensable. Aging Biology is by scientists, for scientists.

Fantastic work by @PassosLab Hanna Salmonowicz @MitosRUs and others. Thanks for including us. Now we have at least 3 cytoplasmic DNAs to think about in senescence- Line1, CCF and mitochondrial. What’s the relationship between them?

Very excited to announce that the final version of this preprint is now published online today at Scientific Data! We hope this resource will be useful to the aging and killifish research community and thank all our collaborators again! nature.com/articles/s4159…

Congratulations to Marcos Garcia Teneche (Marcos G. Teneche), one of our 2024 AGE Early Career Scholars! Marcos is a PhD student Sanford Burnham Prebys studying how age and senescent cells influence cancer development and progression. Congrats, Marcos! #AGEScholars #AGETC #AGE2024

Another great loss for the senescence field.

Registration closes August 12 for this great meeting!

New study led by talented post doc in the lab Aaron Havas : 1) aged tissues at increased risk of cancer due to "precarious balance"; 2) age-activated IFN signaling is an adaptive response to prevent cancer in older tissues, but w/ maladaptive consequence. tinyurl.com/2k4nzs49

Im excited to share my new study where we ID an age-associated increase of tumor suppressor & oncogene activity kept as a "precarious balance" increasing risk of developing liver cancer in older individuals and that activated IFN as a key tumor suppressor. biorxiv.org/content/10.110…

Please read, distribute and decide if you want to sign a4li.org/support-nilar/

So excited to share this enormous piece of work with you! Led by lacroix🅿️a🅿️i while he was here at Johns Hopkins BMB (he’s now an assistant professor Fox Chase Cancer Center ). A thread!! cell.com/cell/abstract/…

Online Now: IL-1 signaling in aging and cancer: An inflammaging feedback loop unveiled dlvr.it/TFb3zB

New paper out📢! Toxic effects of IFN-I in humans has been suggested in patients with rare monogenic autoinflammatory diseases (SAVI, CANDLE, AGS) where IFN-I are elevated. In the absence of specific inhibitors, their causal role has been difficult to prove. We now report benefit