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Tumor reactivity-driven exhausted CD8+ T cells and tolerized CD8+ T cells associate with contrasting immunotherapy responses in human cancers Science Translational Medicine science.org/doi/10.1126/sc…

Rules all PIs should follow | Science science.org/doi/10.1126/sc…

🛜 Looking forward to presenting my #lecture on #spatial #immunology in #Cancer & its #Breakthrough #immunotherapeutic prospects, alongside key opinion leaders & top researchers at ESMO - Eur. Oncology #Immunooncology #Congress! 🗓️cslide.ctimeetingtech.com/immuno2025/att… KU Leuven Research UZ Leuven Leuven.AI

📣#ESMOImmuno25: Check the programme and register today! Connect with global experts and explore innovative therapies that are shaping the future of oncology care. ⏰ Early registration deadline 8 October 2025 🔗 ow.ly/wpZF50W1mNF

🥂Our #CSI lab recently welcomed summer in #Belgium with a fantastic and relaxing #retreat to the #Ardennes #Chimay! 🤞Lucky to have such a fantastic & motivated #dreamteam! jenny sprooten Octavie Demeulenaere Raquel, Isaure, Saurabh Jannes Govaerts Francisca Borges 🌼 & Sien Van den Keybus

Butyrate enhances CD56bright NK cell-driven killing of activated T cells and modulates NK cell chromatin accessibility nature.com/articles/s4143…

Researchers found that butyrate, a gut bacteria byproduct, reshapes human NK cells by altering their epigenetics, boosting virus-fighting genes and cytotoxicity, while shifting them toward a more regulatory-like state. nature.com/articles/s4143…

Butyrate enhances CD56bright NK cell-driven killing of activated T cells and modulates NK cell chromatin accessibility nature.com/articles/s4143…

Low butyrate has been found in ME/CFS patients a couple times, and one of our most reproducible findings is poor NK cell function. Turns out, they’re linked!

Thanks KU Leuven Research KU Leuven Leuven.AI AstraZeneca Oncology at AstraZeneca connect.kuleuven.cloud/news/2657702

#Tumor-associated #macrophages-induced #lncRNA RP11-627G18.1 promotes #breastcancer #metastasis #Genes & #Immunity Springer Nature nature.com/articles/s4143…

#Mapping the role of #cytokine #signaling at #singlecell and #structural resolution in #uveal #Melanoma #Genes & #Immunity Springer Nature nature.com/articles/s4143…

#Polygenic prediction of #cellular #immune responses to #mumps #vaccines #Genes & #Immunity Springer Nature nature.com/articles/s4143…

#Butyrate enhances CD56-bright #NK cell-driven killing of #activated #Tcells and modulates NK #cell #chromatin #accessibility #Genes & #Immunity Springer Nature nature.com/articles/s4143…

Happy to share our latest #review on #neoadjuvantimmunotherapy: an extensive overview of current and emerging data in NSCLC, TNBC, GI + bladder cancers, melanoma and many more: written with close friends and KOLs published today in Nature Cancer MarleenKokLab doi.org/10.1038/s43018…

Metabolites as agents and targets for cancer immunotherapy nature.com/articles/s4157… This new Review discusses the role of metabolic pathways in cancer and immune cells in shaping the tumour microenvironment, and how they can be targeted to improve anticancer immune responses

🚨June'25 #genes & #Immunity issue is out! Springer Nature ⏩nature.com/gene/volumes/2… 🛜Read abt #glioblastoma #immunotherapy #Cancer #hemophilia #antigens #genetics #COVID_19 #lungcancer #lymphocytes #gastriccancer #tumour #microenvironment #Lung #leptin #inflammation #Immunology

S-#nitrosylated #NEDD4 exacerbates #gouty #arthritis by upregulating #NOD1 to induce #pyroptosis #Genes & #Immunity Springer Nature nature.com/articles/s4143…

#Folate #metabolism-associated CYP26A1 is a #clinico #immune target in #colorectal #cancer #Genes & #Immunity Springer Nature nature.com/articles/s4143…

Regulation of #CD4+ T cell #differentiation and #function by #glucose #metabolism #Genes & #Immunity Springer Nature 👉nature.com/articles/s4143…