The Gate lab is proud to share our first manuscript, led by the incredibly talented Natalie Piehl and Lynn van Olst. In this manuscript, we discovered CSF immune system changes that occur with healthy brain aging and cognitive impairment. 1/10 cell.com/cell/fulltext/…

Could the African turquoise killifish hold the secret to the biology of aging? Researchers from the Brunet Lab and Tony Wyss-Coray lab have developed new techniques to study the fish from birth to death to find out. stanford.io/3HT0pkC

🚨 The SNAAP Mock interview schedule is LIVE 🚨 Go forth and book! calendly.com/stanfordneuroa… Below in this thread we will also share some interview resources we shared with our mentors + mentees who filled out our interest form 👇👇

Have you ever done an “omic” (proteomic/transcriptomic/etc) experiment and wondered why we adjust p-values? Or how it works? Are you annoyed that you lose hits and want to avoid this? Want a 🔥 new R pkg for adjusting w/sensitivity? This paper is for YOU! pubs.acs.org/doi/pdf/10.102…

Interested in the African killifish to study aging and 'suspended animation'? 🐟🐟🐟🐟🐠 We have lab Assistant positions open for killifish husbandry and research at Stanford! Great positions before going to Graduate School! careersearch.stanford.edu/jobs/lab-assis…

If you want to be mentored by a fantastic scientist 🔬🥼💻 I highly recommend applying for this position!

What controls the morphology of #myelin sheaths to enable them to fine-tune conduction velocity? TL;DR: Calcium (Ca2+) signaling; a.k.a. nature’s ultimate multitasker! Read our new pre-print to find out more, led by grad student Manasi Iyer! 🧵👇(1/n)

I'm looking for a research assistant/associate to work with me on microglia, hematopoietic stem cells, lipidome, or aging clock. Please feel free to contact me! So many opportunities and projects in the Wyss-Coray lab! web.stanford.edu/group/twclab/c…

I’ve been super into the idea of intracellular molecular recording to measure cell dynamics, but this tech offers an interesting alternative: make the cells give you a sample!

I’m excited to share our new preprint on lipid droplet accumulating microglia in Alzheimer's Disease. [1/4] biorxiv.org/content/10.110…

Congratulations Dr. Hahn and team 🎉 🧪

Excited to share our work published in Immunity! We validated the human genetic findings that loss- and gain-of-function PLCG2 variants have opposite effects on transcriptional mechanisms, altering microglial phenotypes and AD pathology in mouse models. cell.com/immunity/fullt…

A short summary of a long line of research on a new function of oligodendrocytes in brain energy metabolism - a big thank you to the many colleagues that should have also been coauthors. sciencedirect.com/science/articl…

I am thrilled to present our new study out in nature where we measure aging at organ-level resolution in living people with large-scale plasma proteomics + ML! From Tony Wyss-Coray lab, co-led with former grad student Jarod Rutledge 1/12

We have liftoff! 🚀 Excited to share our new work revealing an essential role of the transcription factor SRF in John Haddad, out today PNASNews. Led by the amazing tal.iram and Miguel Garcia in collaboration with Fabian Kern 🦋 @fabianmkern, Tony Wyss-Coray, and their labs.

What Alzheimer noted as fat saccules in glia may have been lipid droplets. They can be induced by Abeta in microglia leading them to release factors that damage neurons. ApoE4 makes things worse rdcu.be/dA6Kh. Congrats Michael Haney Robert Palovics and fantastic team

Congrats to the team again, and thanks to Dr. Andrew Olson for imaging this beautiful #oligodendrocyte #cytoskeleton featured on the cover

Excited to share our new study in nature! We uncover how the vascular glycocalyx—a carbohydrate-rich coating on blood vessels—plays a crucial role in brain health and aging. A Tony Wyss-Coray & Carolyn Bertozzi labs collaboration. 🍭🧠 #glycotime (1/12) nature.com/articles/s4158…