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Ending the covid pandemic might well require a vaccine that protects against any new strains. Researchers may have found a strategy that will work. trib.al/FvPRxyH

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Our paper on immunization and long germinal centers is out in nature! Congrats to the indefatigable and brilliant JH Lee and Harry S ! 🧵 nature.com/articles/s4158… And Free link: rdcu.be/cV2xv

We are thrilled to see our former graduate student, Magnus Hoffmann, receive this award! 🎉 Can’t wait to see what the Hoffmann Lab will accomplish Caltech!

Big week in the Bjorkman lab! Magnus Hoffmann has officially started his independent research in the Hoffmann Lab , Zhi Yang is leaving us for a new Postdoc, and most importantly, Kim Dam has successfully defended her Graduate Thesis! We are so proud of you guys!!

Reminder that the early registration deadline is Nov 18--sign up today! cvent.me/M2DZ0k Wrapping up our Immunoengineering session highlights is Dr. Pamela Bjorkman! And wow, is this work timely and welcome in the wake of the most devastating pandemic of our lifetimes.

Proud.

Efforts to develop a nanoparticle vaccine that protects against many coronavirus variants—a collaboration led by @BjorkmanLab is highlighted—is one of Newsweek's selections for "23 Things to Look Forward to in 2023." newsweek.com/2022/12/30/med…

Colin Mann An incredible effort lead by Magnus Hoffmann from Hoffmann Lab!

Check out our preprint describing the EABR technology, which enables combining features of mRNA- and protein nanoparticle-based vaccines through genetic encoding of self-assembling enveloped virus-like particles (eVLPs)! doi.org/10.1101/2022.1… Collab with The Bjorkman Lab! 🧵(1/n)

Please tune into this week's episode of Science Friday, where our very own Dr. Pamela Bjorkman talks about our lab's efforts to create a Pan-coronavirus vaccine sciencefriday.com/segments/next-…

A new study identified “coldspot” regions conserved across different #SARSCoV2 variants and isolated antibodies able to bind to these regions and protect mice against infection. The Barnes Lab Stanford University USI University 📄: scim.ag/1iW

Great summary (as usual) from Ewen Callaway: The next generation of coronavirus vaccines: a graphical guide nature.com/articles/d4158…

Just posted our pre-print on #vaccine strategy to elicit broadly-neutralising antibodies against different coronaviruses biorxiv.org/content/10.110… Keen to get your feedback, either at bioRxiv or directly. The Bjorkman Lab Jack Tan Alexander Cohen

Final version of our paper on deep mutational scanning system to measure antigenic and functional effects of mutations to full SARS-CoV-2 spike: cell.com/cell/fulltext/… System uses non-replicative lentiviral pseudotypes to safely map effects of thousands of spike mutations.

Now online! ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines dlvr.it/SmrjQy

Check out our new paper Nature Nanotechnology on an improved version of a pan-Sarbecovirus nanoparticle based vaccine. HowarthSci The Bjorkman Lab MRC WIMM MRC TIDU CAMS Oxford Institute. Thanks to everyone involved in this study!

Our publication (cell.com/cell/fulltext/…) about potential effects of original antigenic sin on elicitation of broadly crossreactive antibodies in COVID-19–vaccinated animals injected with mosaic-8b RBD nanoparticles was discussed on MicrobeTV !

Is there a link between #ClimateChange & increasing risk/severity of #wildfire in California--including the still-unfolding disaster? Yes. Is climate change the only factor at play? No, of course not. So what's really going on? [Thread] #CAfire #CAwx #LAfires

1) Since there is a lot of confusion about the reduction of the overhead rate on NIH grants to 15% (see here: grants.nih.gov/grants/guide/n…) I'll do a little tweetorial (or X-torial?) about it.