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The structure of an A. bisporus mannose-binding protein variant reveals that the C-terminal region has an impact on sugar binding and is important for the mannose-binding affinity #AgaricusBisporus #CarbohydrateBindingProtein #LectinLikeProtein doi.org/10.1107/S20532…

This ATP-dependent DNA ligase crystallized in the DNA-encircling conformation, arrested as a step 2 intermediate in the catalytic cycle with the adenylating cofactor transferred to the 5′-phosphate of the DNA nick The University of Waikato 🎓 #RhizobiumPhage #DNALigase doi.org/10.1107/S20532…

Folmer Fredslund et al.: Crystal structure of the sucrose phosphorylase from Alteromonas mediterranea shows a loop transition in the active site #SucrosePhosphorylase #GH13 #Marine DTU @univnantes... #IUCr journals.iucr.org/paper?S2053230…

The structure of the C1 domain of the surface-layer protein SlpM from L. brevis provides new insights into the architecture and evolutionary adaptability of SLPs in Lactobacillus species IUCr #XRayCrystallography #SurfaceLayerProtein #SlpM doi.org/10.1107/S20532…

Thi Yen Hang Bui et al.: Crystal structure analysis of oxygen-induced degradation occurring in rsCherry #FluorescentProteins #CrystalStructures #Degradation ... #IUCr journals.iucr.org/paper?S2053230…

Lucía Giraldo-Ruiz et al.: Structural insights into full-length human fascin1: a target for cancer treatment #HumanFascin1 #Cancer #Metastasis @canalugr... #IUCr journals.iucr.org/paper?S2053230…

The July issue is out! tinyurl.com/y25fxe86 The cover shows a rainbow of protein crystals taken from a Topical Review on 'Preparing for successful protein crystallization experiments'. Take a look at doi.org/10.1107/S20532…

Awarded every three years, the Ewald Prize includes a medal, certificate and financial award. The 2026 Prize will be presented at the Congress in Calgary, Canada, in August 2026 Deadline: 30/11/2025 Details: iucr.org/iucr/ewald-pri…

Andrews, Sakon and Fan: Crystal structures of Escherichia coli glucokinase and insights into phosphate binding #Glucokinases #Hexokinases #PhosphateBinding @uarkansas... #IUCr journals.iucr.org/paper?S2053230…

Patrick Kloskowski et al.: Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13 #SARSCoV2 #NSP13Helicase #NucleotideBindingSite @unigoettingen... #IUCr journals.iucr.org/paper?S2053230…

Features of sample preparation that should be considered prior to biomolecular crystallization experiments are reviewed, as described in the SAMPREP workshop during the 73rd Annual ACA Meeting #Crystallization #XRayCrystallography #StructuralBiology doi.org/10.1107/S20532…

Structural variation in positive subsites in loop regions demonstrating high structural variability suggests potential differences in substrate specificity in family 168 glycoside hydrolases UniversityOfVictoria #GlycosideHydrolases #Fucoidanases #MarineBacteria doi.org/10.1107/S20532…

A crystal structure determination of the S. maltophilia EntB protein revealed it to be an unusual, single-domain form of isochorismatase enzyme. @northwesternu Structural Biology Communications IUCr #StenotrophomonasMaltophilia #Siderophores #Enterobactin doi.org/10.1107/S20532…

M​ichelle Bailey et al.: Structures of Listeria monocytogenes MenD in ThDP-bound and in-crystallo captured intermediate I-bound forms #ListeriaMonocytogenes #MenaquinoneBiosynthesis #SEPHCHCSynthaseMenD @ucnz... #IUCr journals.iucr.org/paper?S2053230…

This study of imidazole glycerol phosphate dehydratase suggests that cryo-EM can be useful in pinpointing the mode of binding small molecules of low mass and mapping protein-ligand interactions #CryoEM #Tuberculosis #HistidineBiosynthesisPathway doi.org/10.1107/S20532…

The structure of an apo unmutated sucrose phosphorylase from Alteromonas mediterranea shows the presence of two major catalytic conformations in the same crystal DTU @univnantes Structural Biology Communications IUCr #SucrosePhosphorylase #GH13 #Marine doi.org/10.1107/S20532…

Thibault Vantieghem et al.: Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening #PWWPDomain #CrystalLattice #CrystalForms ... #IUCr journals.iucr.org/paper?S2053230…

Four structures of rsCherry exhibiting varying degrees of degradation indicate that oxygen-induced degradation of rsCherry predominantly affects the chromophore without altering the protein backbone #FluorescentProteins #CrystalStructure #Degradation doi.org/10.1107/S20532…

The first fully resolved crystal structure of human fascin1 is presented, fully modeling both molecules in the asymmetric unit and offering new insights into its conformational dynamics and structural plasticity @canalugr #Cancer #Metastasis doi.org/10.1107/S20532…