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🌟Exciting news in kidney transplant care! Our study published in Nature Medicine today and presented at the #ATC2024Philly highlights the potential of dd-cfDNA for detecting kidney transplant rejection. This non-invasive method offers enhanced early detection. #KidneyTransplant

"Identification of liver transplant biopsy phenotypes associated with distinct liver biological markers and allograft survival" by Demir et al doi.org/10.1016/j.ajt.…

Une étude vient de démontrer que la biopsie liquide présente un intérêt majeur pour prédire le rejet de la #GreffeRénale 👉 Elle permet d'éviter les biopsies inutiles et invasives tout en détectant les rejets plus rapidement ➡ aphp.fr/contenu/eviter… Hôpital Necker AP-HP

A prospective observational study including 2,882 kidney allograft recipients from 14 transplantation centers in Europe and the US show that cell-free DNA can be used to detect #kidney #allograft rejection Alexandre Loupy @olivieraubert Paris Transplant Group nature.com/articles/s4159…

Une équipe intégrant des chercheurs de l’#Inserm ont mené une étude sur l’intérêt de la #biopsie liquide en tant que technique pour prédire le rejet de #greffe rénale. Lire le communiqué : presse.inserm.fr/eviter-le-reje… Alexandre Loupy

EU~TRAIN large prospective multicentic 🇪🇺 trial 🧐 23 blood biomarkers -> None show association and added value to SOC for detecting rejection🚫AKR1C3 🚫CD3E🚫CD4🚫CD40🚫CD8A🚫CD9🚫CTLA4🚫FOXP3🚫GZMB🚫ID3🚫IL7R🚫MS4A1🚫MZB1, 🚫POU2F1🚫TCL1A🚫TKR4🚫TRIB1🚫AT1R🚫ETAR🚫c3AR🚫C5aR

#Banff2024 #PITOR Université Paris Cité 2024 meeting is a #sankeydiagram festival this year! 😅 Posit PBC RStudio Tips Python Software Foundation SFT JUNIORS ESOTtransplant AmericanTransplantCongress Paris Transplant Group Hôpital Saint-Louis AP-HP

La conférence internationale Banff 2024 s’est achevée vendredi 20 septembre, à l’Université Paris Cité, après avoir réuni 350 spécialistes venus du monde entier. Accueillie à Paris par le Paris Transplant Group (PITOR) de l’université Paris Cité, leader européen en matière de transplantation

Prognostic models are becoming increasingly relevant in clinical trials as potential surrogate endpoints, and for patient management as clinical decision support tools. This study found that competing and noncompeting risk models performed similarly in predicting long-term kidney

Check out our paper JASN_News that assesses the impact of competing risk in prediction models for long term kidney allograft loss. 🎉 to Agathe and Marc Raynaud 🇫🇷 for deep diving competing risk methodology ! Gary Collins Maarten Naesens Kamar Nassim Ilkka Helanterä et al #iBox 🦾

📢 Just published in NEJM and presented at American Society of Nephrology #KidneyWk: Our study, analyzing over 16,000 biopsies from 30+ centers, provides insight into microvascular inflammation in kidney allografts. Alexandre Loupy 🙌 to Marta Sablik Aurélie Sannier Marc Raynaud 🇫🇷 Let’s dive into it 👇

Excited to share our work released in NEJM on kidney-transplant microvascular inflammation. With data from over 16,000 biopsies, we reveal distinct rejection phenotypes linked to varied outcomes—an essential step toward standardized kidney allograft diagnostics. Paris Transplant Group

Une étude menée entre autres par des scientifiques de l’#Inserm a caractérisé pour la première fois des nouvelles formes de rejet de #greffe rénale et leur impact sur la survie à long terme des greffons rénaux. 1/4 Lire le communiqué : presse.inserm.fr/une-etude-inte… Alexandre Loupy

Check out our latest paper just released American Society of Nephrology #KidneyWk many thanks to all our amazing network and collaborators !

Excited to announce our Paris Transplant Group and Necker-Nephrologie-pediatrique participation on "Challenges and Scientific Advancements in Biomarkers for Pediatric Transplantation"! In partnership with @IPTA_Transplant, we're working alongside ESOTtransplant to tackle challenges in pediatric care!

[ 📰 Publication dans le NEJM ] 🔎 Une vaste étude internationale a été conduite à l'institut PITOR (Paris Institute for Transplantation and Organ Regeneration - Inserm U970, Université Paris Cité ) incluant plus de 16000 biopsies réalisées chez 7000 patients transplantés rénaux

📖 This weekend don't miss our Kidney International #ISNFridaySelection: Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN) kidney-international.org/article/S0085-…

Our study on Microvascular Inflammation of Kidney Allografts and Clinical Outcomes is now published in print! 📖✨ Alongside it, a must-read editorial dives into the evolving landscape of antibody-mediated rejection nejm.org/doi/full/10.10… A summary 🧵👇

🔬 Just published in The Lancet: a new Clinical Series on Solid Organ Transplantation, co-authored by experts around the globe. 📖 Read the full Series: thelancet.com/series-do/orga… Thread below 👇 #ESOT2025 Alexandre Loupy Marta Sablik Peter Reese Kiran Khush

📢 Just out in Nature Communications & presented ESOTtransplant ! Our study "Impact of HLA evolutionary divergence and molecular mismatches on AMR of kidney allografts" is now published. 🔗nature.com/articles/s4146… 🙌to Zeynep Demir Carmen Lefaucheur Alexandre Loupy