🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🦠 CORNELL MICRO IS HIRING! To be competitive you do not need a CNS paper, or a K99, or any other fancy stuff you *think* you need to feel ready. You only need a plan to advance your field, be a great mentor, and get funding. Apply!! academicjobsonline.org/ajo/jobs/22752

Spread the word! The Ke lab has two new postdoc openings. We aim to convert first-hand mechanistic understanding of RNA-guided systems into novel genome editing applications. RT please. academicjobsonline.org/ajo/jobs/22875 academicjobsonline.org/ajo/jobs/22877

A happy moment for my dear colleagues Jeremy Baskin and Pam Chang as well:)

Can't wait to check out the coordinates!

Attention: exciting opening in my department! Join us to explore the new scientific unknowns!

Out today Cell Host & Microbe: An expanded arsenal of bacterial immune systems Even if you previously read the preprint, don’t miss a major new result on the bacterial SEFIR domain, a homolog of human immune domains A thread 🧵 1/9 sciencedirect.com/science/articl…

There is still time to apply to the faculty opening Cornell MBG. Broad search. Many #CRISPR folks would fit into one of the emphasis areas: microbial genomics, macromolecular assembly, or synthetic biology! Retweet please. jobs.sciencecareers.org/job/621716/ten…

Glad to see the back-to-back stories on Cas12a2 finally out in Nature. Congratulations to the authors!

We describe a new family of immune protein domains that break ATP to abort viral infection They protect bacteria against phages and also likely function in animal immunity Found in CBASS/NLR/pAgo, plus a new system: Detocs Congrats @FrancoisRousset! biorxiv.org/content/10.110…

What a surprise. Is it used to silence the transposons?

Cool study. Congratulations to the teams!

Cryo-EM structure of the transposon-associated TnpB enzyme nature.com/articles/s4158…

TnpB structure reveals minimal functional core of Cas12 nuclease family nature.com/articles/s4158…

This is beautiful work!

Wow, CRISPR Thanksgiving!

.CornellChemistry researchers take a step toward harnessing #CRISPR gene editing in “targeted, safe and potent” cancer treatment; the enzyme CRISPR-Cas3 could be used to find unique genetic features in cancer cells and shred them. Led by professor Ailong Ke's Lab at Yale MB&B as.cornell.edu/news/shredding…

Ever-expanding new CRISPR tricks to fight against phages!

Thank you for sharing this, Malcolm. I don't think I've missed any CRISPR meeting ever since. Certainly will not miss the coming one:)

My lab has postdoc openings in the following areas: 1) Structural biology and single molecule biophysics; 2) Developing novel genome editing methods; and 3) Protein and RNA engineering. Please share the info with your trainees, and RT please. 🙏 postdocs.yale.edu/yale-postdocto…