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Does the benefit of incretin medications occur due to weight loss alone or is there an additional direct tissue effect of the drug? 🤔 This likely differs by disease. For hypertension, the benefit of incretin medications is primarily driven by weight loss. A mediation analysis

The fourth trimester is a crucial time to connect patients with ongoing care. 🩺 Malamo Countouris directs the Postpartum Hypertension Program at UPMC Magee-Womens Hospital, which provides patients the opportunity to meet with multiple providers, have follow-up questions answered,

Remember to WEAR RED tomorrow - 2/7 - on Wear Red/Go Red for Women Day. Plan your "red" today so you'll be ready tomorrow According to the Center for Disease Control (CDC), the overall leading cause of death for both women & men across all races, origins & ages is heart disease

SGLT2 inhibitors paradoxically have greater cardiovascular protection in older adults compared to younger adults with T2DM, despite producing less of an a1c reduction. GLP-1 receptor agonists were more cardioprotective in younger people. Add SGTL2 inhibitors may not be as

I'm paying attention to almost all of these trials ozmosi.com/market-overvie… We've heard a lot about enobosarm, bimagrumab, MariTide (AMG-133) already and why they might be significant players in the #obesity space Why am I curious about bremelanotide and TERN 601? 👉

Only when 🫀#cardiology🤝 w/🫘 #nephrology can the field of #ADHF move forward w/respect to kidney related entry criteria & endpoints. We 📣for #standardization to allow for real progress. Massive HF Collaboratory effort w/leadership from Maria Rosa Costanzo Mona Fiuzat & 🌟 Jason Feinman, MD

Thrilled to have Dr. Khurram Nasir here with us (back in PGH after 20 years!) for an excellent and insightful Grand Rounds - a tour de force on #CAC and future of #cvPrev! 🫀 UPMC Heart and Vascular Institute Pitt Cardiology Houston Methodist

Now in JACC Journals #JACCHF, VA based registry analysis of KDIGO-defined CKD and outcomes in patients with HFrEF, HFpEF, HFmrEF More urgency to consider disease modifying therapies to prevent GFR decline (SGLT2i, nsMRA, GLP-1a) in pts living with HF? jacc.org/doi/10.1016/j.…

Important new study showing a harmful association of DAPT comprising more potent P2Y12 inhibitors in SCAD, supporting that SCAD with its intramural haematoma is very different from atherothrombotic heart attacks #SCAD #womenheart #heartattack see full paper here EHJ

academic.oup.com/eurheartj/adva…

Bromocriptine treatment and outcomes in peripartum cardiomyopathy: the EORP PPCM registry. Learn more in #EHJ doi.org/10.1093/eurhea… #PeripartumCardiomyopathy #Bromocriptine #EORPPPCMRegistry #WomenHeartHealth @ESCardio European Society of Cardiology Journals

Now that people are checking Lp(a), it is becoming more obvious and accepted. When we published our paper on this, we had a lot of negative reactions because it was not clear if this was clinically relevant or would make people stop taking statins. Bottom line is statins treat

David, nice to hear from you after all these years. I think the likeliest explanation is pts on statins benefit globally, but if Lp(a) is elevated, the overall absolute benefit is less. This can be seen in the placebo groups (on statin) in the recent PCSK9i studies.

At #ACC25, we explored building successful trials through partnerships & innovation. ✅ Unique trial design can = diverse enrollment ✅ Start small, publish, & grow ✅ Industry interest follows proven patient enrollment Thanks to Novo Nordisk & all who joined us! #CardioTwitter

Obesity accelerates cardiovascular ageing . Read more in EHJ doi.org/10.1093/eurhea… #obesity #ageing @ESCardio European Society of Cardiology Journals

In honor of World Preeclampsia Day (ahajrnls.org/3GfN2Mm), we've dedicated a whole issue to the Advance of Pregnancy Hypertension! ahajrnls.org/3Y0ZSnR. Make sure to check it out today!

LIPID METABOLISM IN WOMEN 🧪Lipid profile over life course . LDL, HDL . Lipoprotein(a) 🧪Sex hormones & lipid metabolism 🧪Menopausal transition, hormone replacement therapy ❓What about ✍️body composition/ApoB/Tryglicerides? ✍️gender-affirming hormone therapy? #CardioloED

The hottest controversy for GLP1s is whether it causes meaningful muscle loss 💪 . A newly published study with tirzepatide shows an adaptive response to weight reduction for muscle volume ⚖️ There is a similar amount of muscle volume reduction with GLP1-induced weight loss