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Quantitative Fluxomics of Circulating Metabolites dlvr.it/RdVxvw

advances.sciencemag.org/content/6/33/e…

A new adenosine sensor Ado1.0 developed by Li lab helps Dr. Min Xu's group (ION, Shanghai) to identify how glutamatergic neural activity in basal forebrain during wakefulness contributes to sleep homeostasis through the release of adenosine. Congrats! science.sciencemag.org/content/369/65…

I am looking for MSc, PhD students, postdoc and lab manager to join my lab in Tel Aviv University! We study how experience can continually shape neuronal activity. We use 2pFLIM imaging and gene editing to explore in vivo neuronal protein signaling. Contact me for more details, please RT

8 months!! 🇺🇲❤️🇪🇺

The cross-talk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism | Nature Metabolism nature.com/articles/s4225…

We have known forever that mTORC1 can sense mitochondrial function. Using a combination of CRISPR screening and candidate testing Kendall greatly clarifies the multiple mechanisms involved. Very happy to post the preprint and receive feedback!

7 years in the making, and thanks to my amazing team Alejandro Aguilera Castrejon @bernardooldak Noa Novershtern @itaymaza & collaborators, our new paper is out. description will follow below later nature.com/articles/s4158…

🎊And then there is us (@MaxKatsenelson & Inna Slutsky ) that want to show to mitochondria scientists a neuro-physiological process they might never heard about. Check out our opinion in TINS on #mitochondria #firing rate #homeostasis #neuron #sleep🎊: sciencedirect.com/science/articl…

Profound changes in whole-body metabolism during sleep. Sleep is one of the most fascinating human behavior, where consciousness fades for a few hours, making room for restorative and anabolic processes. cell.com/cell-reports/f…

Neurons need mitochondria not only for making fuel to fire, but also for firing rate stabilization! Maxim @MaxKatsenelson, a brilliant PhD student in my lab, found that IGF1 receptor is crucial for firing rate homeostasis and it does so by regulating mitochondrial calcium.