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Thrilled about this preprint article from Hao Chen & Albert Kim, MD, PhD about USP7 and Hao-Fountain syndrome! You guys had me at "a novel p53-independent ubiquitin signaling pathway." ncbi.nlm.nih.gov/pmc/articles/P… Albert H. Kim Test Account #USP7 #HaoFountainsyndrome Hao-Fountain Syndrome

VERY happy to share THREE papers exploring the genomic, biochemical, and cellular architecture of Schwann cell tumors published in Nature Communications today from RaleighLab members John Liu, MD PhD and Tim Casey-Clyde, from former lab member Vasudevan Lab, and from Albert H. Kim! 1/5

First, RaleighLab shows that functional interactions between neurofibromatosis tumor suppressors underlies Schwann cell tumor de-differentiation and treatment resistance, revealing new therapeutic strategies for resistant tumors. 2/5 nature.com/articles/s4146…

Second, Albert H. Kim shows that vestibular schwannoma cells resemble a nerve injury-like state. 3/5 nature.com/articles/s4146…

Third, RaleighLab shows that epigenetic reprogramming shared the cellular landscape of schwannomas, and reports a novel function genomic technique for single-nuclei RNA/ATAC/CRISPRi-perturbation sequencing (snARC-seq). 4/5 nature.com/articles/s4146…

In sum, many advances in our understanding of these common peripheral nervous system tumors, and some new techniques with broad relevance ! Exhilarating to work with Vasudevan Lab John Liu, MD PhD Tim Casey-Clyde Albert H. Kim and many others on these papers! UCSF Neurosurgery . 5/5

Too fun collaborating with you, my friend. Lots of hypotheses to follow up on from our work! BCM Neurosurgery @WashuBTC

So proud of our trainee and now faculty colleague, Bhuvic Patel, MD, on this collaborative study with Sahm Lab on pituitary carcinoma NASBS meeting. @WashuBTC WashU Med Taylor Family Department of Neurosurgery

Repetitive sequences make up much of the human genome and have been implicated in #cancer development. In the latest edition of Science Magazine, Dr. Dimitrios Mathios (Dimitrios Mathios) and colleagues (1/2)

The #BrainTumorCenter seminar series is back! Join us on 4/3 at 8:30 a.m. CST for a talk by Aaron Diaz, PhD (Diaz Laboratory) about single-cell studies of #braintumor heterogeneity. Siteman Cancer Center Test Account

#DivisionOfNeurotech WashU Med Taylor Family Department of Neurosurgery Congrats all!!

The #BrainTumorCenter seminar series welcomes Christine Brown, PhD, from City of Hope as she discusses "CAR T Cells for #Glioblastoma. Join us in Moore Auditorium on 5/1 at 8:30 a.m. for breakfast & conversation. Siteman Cancer Center

Great anterolateral and endoscopic endonasal approach dissections by trainees! Looking forward to Bhuvic Patel, MD as a skull base colleague. @WashuBTC

Today is World Brain Tumor Day, an opportunity to highlight the Brain Tumor Center at Siteman and the exceptional Test Account physicians and researchers who provide exceptional care grounded in cutting-edge research and clinical trials. Learn more: l8r.it/sPlS

Excited, our collaboration with WashU Med Taylor Family Department of Neurosurgery to look at rare but devastating multiply recurrent meningiomas is out! Science Advances BCM Neurosurgery From the Labs at Baylor College of Medicine Dan L Duncan Comprehensive Cancer Center Albert H. Kim Tiemo J. Klisch Sangami Pugazenthi Collin English Akdes Serin Harmanci science.org/doi/10.1126/sc…

What makes some #meningiomas more aggressive and harder to treat than others? A Patel Akash Patel, Albert H. Kim, Tiemo J. Klisch, Sangami Pugazenthi, Collin English, Akdes Serin Harmanci et al have answers. Science Advances BCMHouston WashU Med Taylor Family Department of Neurosurgery BCM Neurosurgery bcm.edu/news/study-inc…

.Matthew Ishahak and team, including Jeffrey Millman & Albert H. Kim, developed engineered #glioblastoma (GBM) #organoids harboring GBM subtype-specific oncogenic mutations to study the underlying transcriptional regulation of tumor progression. 👉 bit.ly/4arbBBb

Congrats to Hao Chen and the team on his paper on Hao-Fountain syndrome. A fantastic collaboration with Azad Bonni and Cole Ferguson. WashU Med Taylor Family Department of Neurosurgery cell.com/cell-reports/f…

Please check out our collaborative meningioma paper with Akash Patel helmed by Bhuvic Patel, MD Sangami Pugazenthi on the molecular basis of radiation resistance in necrotic grade 2 meningiomas. Great job, team! academic.oup.com/jnci/advance-a…

Congrats to Julie M Silverstein, Medical Director-WashU Pituitary Center, and team The Brain Tumor Center on randomized trial that definitively shows fluid restriction after endoscopic endonasal surgery for pituitary tumors decreases the most common post op complication. Neuro-Oncology now!