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One of the fun things about working at Novo Holdings is periodic updates on the thousands of projects supported by the Novo Nordisk Foundation. Small one caught my eye today -- is milk or yogurt better for your bone health? The answer is yogurt. Stud…lnkd.in/dvJsYYEs

Participated in a very inspiring round-table discussion at The World Bank today on #antimicrobialresistance. While many stories and statistics were bleak, real solutions exist! Chart is a fantastic example -- It shows the amount of antibiotics used in…lnkd.in/eAUbJiQR

Snapshot of grants awarded by the Novo Nordisk Foundation in 2023. lnkd.in/eSi-aBWT

A couple of recent positive papers on coffee and tea: Coffee: Higher coffee intake leads to greater microbiome diversity (good), higher levels of Faecalibacterium (good anti-inflammatory), higher levels of Alistipes (good inhibitor of harmful bacteria),…lnkd.in/eapb7yHk

The Presidential Advisory Council on Combating Antibiotic Resistant Bacteria (#PACCARB) released this report: Preparing for the Next Pandemic in the Era of Antimicrobial Resistance. Link here: lnkd.in/emu7MzTz There are 14 recommendations. Highli…lnkd.in/ezHhP7rP

Congrats to team Vedanta Biosciences, Inc. on their >$100m financing! Extremely impressive in the anti-infectives space these days and a testament to the promise of the platform. lnkd.in/dQwj6f7i

Wowst! Big congrats to Seres Therapeutics on their approval of their oral microbiome pill against c.diff infections. And the product (previously called SER-109) has been named Wowst. Wowst. lnkd.in/eGQv8B-K

The PASTEUR Act has been re-introduced to congress. Front page story in the The Wall Street Journal today (article behind paywall). lnkd.in/edShCpHk

Act now: Send a message to your members of Congress urging them to include the PASTEUR Act in the reauthorization of the Pandemic and All Hazards Preparedness Act (PAHPA) this year. The bill, supported by a diverse range of grou…lnkd.in/eA_YXYNC lnkd.in/eV_dJpuM

Great synopsis of an amazing week in AMR by John Rex and Kevin Outterson. lnkd.in/dif-gt8c

New paper show that the evolution of colistin resistance increases bacterial resistance to host AMPs (our innate immune system). In other words, misuse of antibiotics not only degrades efficacy of the antibiotics over time but also degrades our natural h…lnkd.in/ep8mqFQQ

The European Centre for Disease Prevention and Control (ECDC) warns of "severe consequences" if spread of resistant bacteria is left unchecked. Number of carbapenem-resistant e.coli infections jumped from 2 to greater than 200 from 2013 (last survey) t…lnkd.in/exPG5JTX

Congrats to Entasis Therapeutics/Innoviva Specialty Therapeutics, Inc. on the approval of Xacduro (SulDur) against resistant Acinetobacter baumannii lung infections. Proud that Novo Holdings invested to support making this drug av…lnkd.in/ejtNuNV9 lnkd.in/ebMcVghB

New Delhi metallo-beta-lacatamases (NDM-5) is a bacterial resistance mechanism rendering carbapenems, our last-resort class of anti-biotics, useless. Several different sequence types are now rapidly spreading in Europe. #antimicrobialresistance is not a…lnkd.in/eUSNrH9a

The promise of synthetic biology is largely dependent on regulations being an enabler as opposed to a barrier. In particular, Europe is in the process of shooting itself in the foot by approaching the issue from an outdated regulatory framework. Five gr…lnkd.in/eDD7XPSu

Synthetic biology holds many promises but may also have been hyped beyond the immediately addressable problems. The linked article urges the investment community to return to a focus on engineering first principles in solving spec…lnkd.in/eKipGXrE lnkd.in/eQyjvRDd

Feeding fluoroquinolones to chickens is a terrible idea and unfortunately has consequences. Story from the UK. lnkd.in/eCjKMNMh

TIME 100 most influential companies includes our portfolio company LanzaTech. Congrats Jennifer Holmgren and team. Oh, and Novo Nordisk is also on the list. lnkd.in/eumPk6fQ

Congratulations to Qpex Biopharma and Shionogi Inc. on this $100m acquisition. Michael Dudley and team have been pioneers in the anti-infective space and it is wonderful to see this recognized by Shionogi. This follows on Shionogi's successful worldwide…lnkd.in/eiNX_fV8

Hoping for a full recovery for Madonna and everyone else with serious bacterial infections. yahoo.com/entertainment/… CARB-X exists so everyone has access to what they need. The clinical pipeline is thin; CARB-X is rebuilding the preclinical pipeline for the future. Working to Fight AMR