🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Let's continue to stand together in the fight against ALS. #LouGehrigDay 🎙️ Sarah Langs

Very excited to see our manuscript on the Neurolipid Atlas online @S_Koppes_Hertog @vanderkantLab @Martingiera! Big thanks to all collaborators! biorxiv.org/content/10.110… neurolipidatlas.nl A thread:

The Rothstein lab is seeking postdoctoral candidates! Please see the attached document for more information and direct all your inquiries to the email address below. Please RT!

Our thoughts on the two recent C9 ASO trials and where we go from here as a field.

Our paper on cryptic splicing-controlled protein expression, which we hope will inspire safer and more adventurous gene therapy approaches for ALS and FTD, has been published in Science Magazine science.org/doi/10.1126/sc…

Out Science Magazine! New tech to activate ALS gene therapies only in the right cells at the right time - Increased safety to have more options for ALS. We do it by taking advantage of cryptic splicing. science.org/doi/10.1126/sc… UCL Queen Square Institute of Neurology The Crick Oscar Wilkins Max Z. Y. J. Chien

PhD Prize, celebrate the outstanding achievements of doctoral researchers 🥇 Ashling Giblin (Adrian Isaacs Lab) & Dorothea Boeken (@klenermanlab)

🧬 Genetic differences that contribute to how long a person will live and their risk of Alzheimer’s disease have been identified in a new study led by Dervis Salih (UK DRI at UCL ) in collaboration with @ValentinaEPriceValen (UK DRI at Cardiff) & Prof Sir John Hardy (UK DRI at

Our new paper is online: Human longevity and Alzheimer’s disease variants act via microglia and oligodendrocyte gene networks. academic.oup.com/brain/advance-… Brain UK Dementia Research Institute UCL Brain Sciences UCL Queen Square Institute of Neurology

Our latest paper is out in Nature Communications, detailing a new CRISPR-CasRx approach for reducing sense and antisense C9orf72 repeat pathologies. Adrian Isaacs Lab Adrian Isaacs UK Dementia Research Institute UCL Queen Square Institute of Neurology nature.com/articles/s4146…

Tofersen treatment leads to sustained stabilization of disease in SOD1 ALS in a “real-world” setting onlinelibrary.wiley.com/doi/full/10.10…

Hmm. There are two errors in this, and also the new 15% limit is way too low. And finally this is an unintentional call for communism. (1) First error. This charge isn’t for “overhead”. It does include overhead, but it also includes “General & Administrative” costs. For

Excited to share our new work describing multiple phenotypes associated with full-length ATXN2 expansions, including autosomal dominant ALS. doi.org/10.1038/s41431…

🙏 Please share and help us spread the word! It means a lot! 🙂 We are looking for individuals who are gene carriers of ALS and currently asymptomatic for an important study! Learn more about this research study here: everythingals.org/asymptomatic-s… #als #alsresearch

Research from the UK Dementia Research Institute at UCL features LLL-funded Postdoc Alex Cammack. It showed an increase in fatty acids in the brain is associated with a reduced risk of developing MND/ALS. Read more about this important study: livelikelou.org/news/cammack-p…

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Honored to received this award from FTDUK and Alzheimer's Society For Researchers! It was a wonderful meeting with great talks and fruitful conversations with colleagues and collaborators! FTDtalk

Join the Hallegger Lab in Oxford. A post-doc position available to develop neuronal cell models to characterise how TDP-43 aggregation leads to its dysfunction in MND. Highly collaborative project funded by My Name'5 Doddie Foundation My Name'5 Doddie Foundation Please repost and share widely!

We’re proud to support Dr Stephanie Fowler and her team with a major project. They’ll be developing new treatments targeting tether proteins to prevent tau spread. Findings from this study could help diversify treatments for tauopathies.

Today, on #RobBurrowDay, we celebrate the life of Rob Burrow. He was a warrior in every sense - massive in heart. He tackled every challenge on and off the pitch with the same fearless grit. Rob never stopped fighting, and never stopped smiling. We are forever grateful 💙