Not everything ends up in the cover but can still highlight great science. This was an interesting project to combine two nature papers showing mitochondrial mtDNA and RNA release in the kidney and macrophages. Groundbreaking work by FrezzaLab PrudentLab @RyanLab_MBU et al.

Honoured to be a small part of this important discovery led by the fantastic Tristram Ryan demonstrating the anticoagulant capabilities of DMF and 4-OI, published in Nature Communications. Congrats!

Immunometabolism community: We seek a postdoc to work at the intersection between immunity, metabolism, and inflammation within a unique multidisciplinary consortium. Please get in touch with me if you are interested! This is going to be very exciting!

Happy to share our work showing that the NRF2 activating compounds, DMF and 4-OI, induce the secretion of the anti-inflammatory protein Annexin A1 from macrophages! Ciana Diskin Juliana Escher Toller Luke O'Neill doi.org/10.4049/jimmun…

Scientists of Twitter! The world needs more reminders that we’re living breathing human beings Shane O'Carroll 🇮🇪🤕 Christian Peace 🇮🇪🇺🇸 Tristram Ryan 🇮🇪🏳️‍🌈 Alex Hooftman 🇳🇱🇬🇧 Hauke Weiß 🇩🇪🇪🇺 #internationalscientists Quote tweet this with a picture of you doing not-science

Alex Hooftman, Christian Peace and I wrote a short open access commentary on the role of #mitochondria and nucleic acid signalling in inflammatory disease. Check it out if the field is of interest to you and your research 👇👇 onlinelibrary.wiley.com/doi/10.1002/ct…

Delighted to share our latest piece all about how the Krebs cycle enzyme Fumarate hydratase regulates immunity from Luke O'Neill, Shane O'Carroll, and myself out now in Trends Cell Biology authors.elsevier.com/a/1i2VJ_LvCM5J…

#IUIS2023: brilliant talk by Luke O‘Neill Luke O'Neill drawing our attention to the most important (and our favorite) organelle! #mitochondria #immunometabolism

Are you interested in the field of #immunometabolism? Check out the final version of our (Alex Hooftman Christian Peace) latest review that discusses the topic of metabolite signalling in the context innate and adaptive immunity 👇 karger.com/jin/article/15…

Alessia Zotta Luke O'Neill and I wrote a review on the most up-to-date research on the role of the ETC in immunometabolism. Be sure to check it out ✅ We discuss the link between forward electron transfer, ROS and the NLRP3 activation… authors.elsevier.com/c/1inFr5Eb0Rxn…

Immunometabolism lovers,the review I wrote with Maureen Yin, PhD and Luke O'Neill for Trends in Immunology is out!🤩📚We focused on the role of ETC in shaping innate and adaptive immune response and how ETC inhibitors could potentially be used as a future treatment for immune-mediated disease.

Very excited to share that in a few short weeks I will be starting as an Assistant Professor at Western University in Physiology and Pharmacology Phys Pharm! If you are interested in immunometabolism and metabolic disease please reach out! Hiring at multiple positions!

🎉🎉🎉Congratulations to Andrea Ablasser who has won the Paul Ehrlich and Ludwig Darmstaedter Prize Paul-Ehrlich-Stiftung with Glen Barber Ohio State and Zhijian J. Chen UT Southwestern Medical Center! 🏆🏆🏆 go.epfl.ch/aapeld2025

Excited to share a new paper from my PhD work along with Shane O'Carroll from the Luke O'Neill lab on how the metabolite itaconate regulates IFN, out today in Nature Metabolism (nature.com/articles/s4225…) (1/n)

🚨🔬Excited to share our new paper now out in Nature Microbiology! Using Tn-seq + live imaging in engineered airway organoids, we explored the fitness tradeoffs P. aeruginosa faces while growing and surviving antibiotic treatment on the mucosal surface. 🔗 rdcu.be/dX4RR

Had a cracking time meeting all of the EMBO Fellows EMBL in Heidelberg. Some amazing science being done across Europe and further afield! Also very grateful to EMBO for funding our research over the last few years #emboat60

🎉🎉🎉Congratulations to Andrea Ablasser who has won the 2024 Liliane Bettencourt Prize for Life Sciences from Fondation Bettencourt Schueller! Read more 👉actu.epfl.ch/news/andrea-ab…

Thrilled to share the work of my PhD,out in Science Advances!🥳We discovered that complex III regulates IL-10 production in macrophages and its targeting decreases tumor growth in mice🧫Grazie a Luke,LON Lab & collaborators🔬 #immunometabolism #lover👇 science.org/doi/10.1126/sc…

Massive congratulations to Alva Casey on her first author paper from her PhD: 'Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation' #immunometabolism

Are you interested in #immunometabolism but not sure where to start? Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona (Molecure) and Luke O'Neill (Trinity College Dublin), available now. shop.elsevier.com/books/metaboli… (1/n)