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Bubble artist Ivanna Orlova creating entire world by bubbles

Engineering bacterial cell morphology for the design of robust cell factories "physical, chemical and genetic approaches to alter cell size and shape" sciencedirect.com/science/articl…

NEWS&VIEWS | M Bartez, D Chen (UC Berkeley): The mitochondrial unfolded protein response controls the mesenchymal-to-epithelial transition during the acquisition of #pluripotency. 🧫✨ nature.com/articles/s4225…

Integrator complex collapse: A mechanistic route to integrated stress response and disease dlvr.it/TLSCgg

We're one, but we're not the same We get to carry each other, carry each other – U2

YAP maintains the dynamics of TDP-43 condensates and antagonizes TDP-43 pathological aggregates | Nature Cell Biology nature.com/articles/s4155…

Just as medical school curricula include histology & pathology atlases, we move toward single-cell spatial omics atlases of human tissue & disease. The Spatial Atlas of Human Anatomy (SAHA) is a subcellular-resolution reference atlas of healthy adult gastrointestinal tissue👇

This should be required reading by all graduate students and postdocs | A brief guide to statistical analysis of grouped data in preclinical research nature.com/articles/s4225…

The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance dlvr.it/TLThm4

Not all chemokine signaling is about cell migration! In mouse erythroblasts, CXCL12-bound CXCR4 enters the nucleus to control gene transcription, trigger calcium bursts, and drive red blood cell formation—especially enucleation. 🔗 science.org/doi/10.1126/sc… #chemokine #CXCR4

1/ You tested 10,000 genes. 500 are significant (p < 0.05). Exciting? Maybe. But if you used raw p-values, you just got played by randomness. Let’s talk FDR.

Virtual staining offers a promising approach to map dynamic cellular systems across various cell types + conditions, broadening the scope of live-cell imaging. Congrats to Shalin Mehta & the team at #CZBiohubSF 🎉🙌 bit.ly/4jZJCvg

🚫 No dyes. No bleaching. 🔬 Just AI + label-free microscopy = vivid virtually stained images New in Nature Machine Intelligence: A deep learning model that enables robust virtual staining across microscopes, cell types & conditions. #CZBiohubSF Shalin Mehta explains:

Today Arc Institute releases State, our first perturbation prediction AI model and an important step towards our goal of a virtual cell State is designed to learn how to shift cells between states (e.g. “diseased” to “healthy”) using drugs, cytokines, or genetic perturbations

This is wild! Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol) Nature Chemistry nature.com/articles/s4155… nature.com/articles/s4155…

NEW content online! Endoplasmic reticulum stress responses in anticancer immunity bit.ly/4ei3dFN

Protein folding stress transcriptionally reprograms muscle metabolism Jacob Paiano, Mujeeb Qadiri, Suhasini Sharma, Yanhui Hu, Norbert Perrimon doi: doi.org/10.1101/2025.0…

A large-scale analysis of U.S. water quality data reveals that most toxic chemicals remain poorly characterized or undetected in routine monitoring. The findings in Science suggest that the true scale of chemical risk to biodiversity and ecosystems may be significantly

The brains of people writing an essay with ChatGPT are less engaged than those of people blocked from using any online tools for the task go.nature.com/4kbyTy7

Register today for the Virtual Cell Challenge and use AI to solve one of biology’s most complex problems. Announced in Cell, the competition is hosted by Arc Institute and sponsored by NVIDIA, 10x Genomics, and Ultima Genomics.