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Our latest smartcell paper is out, combining #synbio & tissue engineering to treat #rheumatoid #arthritis! We made a living implant that senses inflammation & then delivers cytokine inhibitors on demand (here is the 3D woven implant w/cells via nanoCT!) science.org/doi/10.1126/sc…

Press release on our new study, showing we can treat RA in mice using genome-engineered cells that release biologic drugs when they sense inflammation. Great work by Yun-Rak Choi, Kelsey Collins & many other members of @guilak_lab! medicine.wustl.edu/news/rheumatoi… science.org/doi/10.1126/sc…

So excited that two of our papers made the list of basic research Year in Review at #ACR21! Congrats @guilak_lab members Whasil_URochester MaybeItsBob Alireza Savadipour Kelsey Collins Lara Pferdehirt ali ross Chia-Lung Wu Natalia Harasymowicz @jbrunger and all co-authors! @WUSTL_Rheum

Enjoying the ⁦⁦WashU MRC⁩ holiday party - happy holidays everyone! But the real question is where is flat Matt? ⁦Farshid Guilak⁩ ⁦WashU Ortho Research⁩ ⁦@WashU_BMD⁩

It took me 21 hours to make it to Tampa for #ORS2022 so please come and check out my poster (599) today which is titled as “PIEZO1 Mechano-sensitivity in Chondrocytes Is Modulated Through L-Type and T-Type Voltage Sensitive Ion Channels”. WashU Ortho Research The Guilak Lab Farshid Guilak

Congratulations to all elected to National Academy of Engineering in 2022 - including our own Farshid Guilak of WashU Ortho Research WashU McKelvey Engineering The Guilak Lab AIMBE and former editor in chief of Journal of Biomechanics (20 yrs). Recognition for a career of innovation and excellence in research & mentorship! 🎉🙌🙌🎈

Please join me June 13, 12pm CT for a webinar on my favorite topic: “I was trained how to do everything but run a lab!” The lecture is free on the AOCConnect platform. Just register (no cost) as a researcher: aoc-ortho.com & the info will be sent from there. (1/3)

Excited to share our new paper in AJP-Cell Physiology about the role of PIEZO channels in the musculoskeletal system. Huge thank you to @daniel_r_palmer, Farshid Guilak and all the co-authors that helped us in putting this paper together! The Guilak Lab

Excited to share the most recent work from my PhD work! Great collaboration with Leanne Iannucci, Alireza Savadipour, Farshid Guilak, and Lake Lab. Huge shout to WashU MRC as the journal cover photo was helped made possible for our wonderful histology core! faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

Stellar work led by Garrett Easson on the role of #TRPV4 in the mechanobiology of the intervertebral disc! A great collaboration among WUTangLab Lake Lab & @guilak_lab! Plus we have two articles and the cover of one of our absolute favorite journals, FASEB J FASEB!

We engineered flexible, injectable cartilaginous agarose gel rods that deliver 🐭 iPSC smart cells, the @guilak_lab cell-based anti-cytokine therapy. This longterm, living therapeutic implant is delivered using an non-invasive approach Gels MDPI: bit.ly/3kdCZwA Farshid Guilak

Out latest by Amanda Daniel, PhD on the molecular basis of childhood skeletal malformations is now out! She & @chialungwu created #CRISPR-edited #iPSCs to show mutations in #TRPV4 disrupt normal cartilage hypertrophy as a mechanism for dysplastic bone growth. elifesciences.org/articles/71154

The Role of #PIEZO #IonChannels in the Musculoskeletal System: ow.ly/SZeb50NcHCF #review #mechanobiology Farshid Guilak Kelsey Collins Alireza Savadipour @daniel_r_palmer Erica Ely ArinOestreich Feini (Sylvia) Qu Jackie M. Garcia

Congrats to all the best poster awardees at the WashU MRC annual symposium, particularly our fantastic @guilak_lab graduate students, Alireza Savadipour Alireza Savadipour and Amanda Cimino!

Excited to share that my 3rd first-author paper on the gating mechanisms of #PIEZO1 is now published in PNASNews! Grateful for the opportunity to contribute to the field and grateful to my colleagues for their invaluable contributions.Farshid Guilak The Guilak Lab pnas.org/doi/10.1073/pn…

Today, Dr. Farshid Guilak spotlighted a new publication his team put forward - on smart cells that have been engineered to help patients control inflammation caused by arthritis. Thanks to FOX2now! Learn more: youtube.com/watch?v=QkzBMI… #kids #hope #research #arthritis

Congrats to the latest The Guilak Lab PhDs, Alireza Savadipour, Neda Rashidi, and Zainab Harissa!

Professor Farshid Guilak: PIEZO1-Mediated #Mechanotransduction Regulates Collagen Synthesis on Nanostructured 2D and 3D Models of Fibrosis Farshid Guilak The Guilak Lab WashU Medicine Shriners Children's WashU Center of Reg Med WashU McKelvey Engineering sciencedirect.com/science/articl…

Congrats to Dr. Neda Rashidi on her paper just out in Acta Biomaterialia showing the role of Piezo1 in regulating collagen synthesis and fibrosis by adipose stem cells! w/Natalia Harasymowicz Alireza Savadipour Nancy Steward, Ruhang Tang, & Sara Oswald

Check out our latest paper, where we explore the role of Omega-3 and Omega-6 fatty acids in influencing cell membrane properties and the #mechanosensitivity of #chondrocytes. #Research #FASEB