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Viruses can impact organelles in host cells. So why does this make neighboring cells more vulnerable? jared toettcher and Ileana M. Cristea are making new tools to monitor and manipulate organelle connections at a distance from infection sites. #FrontierScience alleninstitute.org/division/front…

Our neural dynamics team is hiring for a research associate and scientific project manager! learn more about the open positions: alleninstitute.org/careers/jobs/?…

On this day in 2020, we launched Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) consortium with UW Medicine and KP WA Research. Since its launch, we've continued to expand our atlas of datasets and resources - all free and open to everyone: lnkd.in/dDYtRY-G

🧬 Allen Institute scientists have developed a precise genetic toolkit that can target the exact nerve cells destroyed by ALS and potentially deliver therapies where they are needed most. This discovery could dramatically speed up the quest for a cure: bit.ly/4k9ZyLA

In this piece of brain tissue the size of sand grain are 200,000 neurons and nearly 2.5 miles of axons. While it may seem small in size, it was previously thought impossible to map. The road to this beautiful image is both a scientific and human triumph: alleninstitute.org/news/scientist…

Our #CellLineOfTheWeek is centrin 2 - illuminating the centrosome! 🧫✨ Our high-quality stem cell lines & plasmids are available for just the cost of shipping to reduce the barriers to scientific discovery. 📦 Distributed by Coriell Institute & Addgene.

DYK around half of the brain is not made of neurons? Among the other half is the octopus-like microglia. In this visualization by our Electron Microscopy team, microglia (green) wraps around a pyramidal cell (blue), one of two types of excitatory neurons in the brain.

Did you make a cool #OpenScience tool using Brain Map? Submit it to our community tools page! Tools should use Brain Map resources, extend the use of data, provide new ways to access and analyze data, or support educational use. Learn more and submit: portal.brain-map.org/explore/toolki…

Forget how your biology textbooks depicted the endoplasmic reticulum. @hhmijanelia scientist Andrew Moore used our open graphics tool AGAVE to create this image showing the ER's outer membrane. The tool borrows animation studio techniques to create realistic light sources.

One in 500 people have hypertrophic cardiomyopathy – the most common genetic heart condition in the world. To accelerate research, we've developed cell line collections that carry mutations seen in this disease and made them available for just the cost of shipping.

Have you used our datasets, atlases, protocols, cell lines, and other #OpenScience resources in your research or classroom? Tell us about it! Share your story at bit.ly/opensciencesto… Select stories will be shared during #OpenScienceWeek and beyond.

Most neurons are excitatory, but some do the opposite and dampen the activity of other neurons. In this visualization by our Electron Microscopy team, an axon (red) sneaks its way in between a satellite microglia (blue) and an inhibitory neuron (gray).

Peroxisomal membrane protein is our #CellLineOfTheWeek! 🧫 Our hiPSC lines and plasmids are available at-cost to accelerate discovery. 📦 🛒 Browse our stem cell lines at Coriell Institute and plasmids at Addgene. #OpenScience

Happy #4thOfJuly! We hope you have a fun and safe holiday. 🎆🇺🇸 If you find yourself in South Lake Union for the festivities, keep an eye out for our red, white, and blue lights! #FourthOfJuly #IndependenceDay

The fireworks in your mind. 🧠✨ This sparkling video shows the neurotransmitter glutamate being released into synapses, made possible by an indicator developed by Abhi Aggarwal, Kaspar Podgorski, and team. #HappyNewYear #NYE

OTD in 2017, the Allen Discovery Centers for Human Brain Evolution (UW Medicine, Caltech, University of Basel) and Cell Lineage Tracing (Harvard Medical School, Boston Children's) were founded. 📸 Reich Lab

Brain donation is critical to understanding brain diseases like Alzheimer's. The BRaIN Lab at University of Washington is looking for possible donors who are 18 years or older and diagnosed with a life limiting illness. More info at dlmp.uw.edu/research-labs/…