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Super excited to announce that we’ve just submitted the latest Liau Lab ~manuscript~! Tldr: we used base editors + a methylation reporter to do a mutational scan of DNMT3A, a key cancer gene. Highlights below, but check out our preprint at biorxiv! biorxiv.org/content/10.110…

Today we're thrilled to bring you a special spotlight of one of our HWIC x Harvard Chem Club pairings! "We never stop being a mentee and it's never too early to be a mentor" -Jen Heemstra Read more about Olivia and Christie at harvardwic.org/spotlight

Incredible work from Liau Lab led by Allison Siegenfeld and Shelby Roseman developing a new method called LIMe-Hi-C to discover Polycomb-Lamina antagonism! Congratulations all!!

Congratulations Stephen Kissler!! CU Boulder 🦬 is so lucky to have you!

Congratulations to Nicholas Lue, Emma Garcia and the the DNMT3A team Liau Lab! Check out this paper for a tour de force in base editing tiling mutagenesis combined with an activity based reporter all followed up with rigorous cellular and biochemical validation!

I want to share an inspiring teaching experience I had this semester. I had a privilege to teach biochemistry to Emily PharmFatale who can’t see the structures like you and I can. At first I was skeptical cause I thought that chemistry is highly visual.

Thank you Stuart Schreiber! I would not have become the scientist I am today without your example, support and mentorship over all of these years. Thank you for opening the door to chemistry and chemical biology to me and so many other women scientists!

Check these amazing preprints from my PhD lab, Liau Lab! Congrats to megan, Olivia, @clee_bio, Pallavi Gosavi, @proteinnns and Brian Liau! Truly a tour de force of chemical biology!