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📢 How can we identify cell lineages from any scRNA-seq dataset ? Check our paper: nature.com/articles/s4146…. Very proud of massive amount of beautiful work by Almut Eisele, A. Dormann + fantastic collaboration with @MTarbier and Pelechano lab. A 🧵

actu.epfl.ch/news/a-new-too…

Second postdoc opening on our #ERC synergy project with gagneurlab  and Kevin Verstrepen . If you want to do RNA biology at scale combining genomics, synthetic biology and Machine learning. Join us at Karolinska Institutet SciLifeLab  Deadline 2024-06-15 ki.varbi.com/en/what:job/jo…

Hello Berlin students, we are looking for a motivated student assistant to support our research team at @berlinnovation and MDC-BIMSB: karriere.charite.de/stellenangebot…. Please apply by July 20! What we do: bihealth.org/en/research/re… and mdc-berlin.de/ludwig Retweets welcome 🙂

📢 To maintain proteome homeostasis, cells need to coordinate the production and elimination of proteins. How does it work? Check out our new preprint: biorxiv.org/content/10.110… A 🧵

Got out of the nucleus! Tested ~30,000 tiles from human RNA-binding proteins, found lots of domains that downregulate RNA&built an inducible synthetic RNA-binding protein for keeping target RNA at constant intermediate levels: biorxiv.org/content/10.110… So many follow-up projects!

Same cell type, same trans environment, same sequence—different expression pattern. Locking in of stochastic differences into epigenetic memory. I just think this is so cool!

Cancer cells often harbor oncogenes outside chromosomes on extrachromosomal DNA (ecDNA), which is unevenly inherited by dividing cells. Today we report in nature that collectives of ecDNAs are inherited together by dividing cancer cells. 1/ nature.com/articles/s4158…

EMBO workshop on Single cell Lineage Tracing! Sept 18-21 in Sant Feliu, Girona, Spain. Registration is OPEN!!!!! Tons of opportunities for talks are still available (including full length ones). meetings.embo.org/event/25-linea… #EMBOlineagetracing

Happy to share our paper describing SPACE-seq - a new approach to spatial multiomics and lineage tracing - out today in PNASNews! 🧵(1/5) pnas.org/doi/10.1073/pn…