Dr Amar Puttanna 🎸 (@amarput) 's Twitter Profile
Dr Amar Puttanna 🎸

@amarput

EPCA winner|QiC award DIADEM| @BrJCardiol|Diabetes Consultant-frailty, ageing, dementia, oral health, sustainability, cardiovascular| @GoggleDocs|tweets my own

ID: 830102078320152576

linkhttps://www.rcplondon.ac.uk/about-rcp/whos-who/people/dr-amar-puttanna calendar_today10-02-2017 17:12:12

15,15K Tweet

3,3K Followers

1,1K Following

Prof Kamlesh Khunti (@kamleshkhunti) 's Twitter Profile Photo

GRADE Trial Weight gain associated with worse glycaemic control & increased risk of cardiovascular and kidney outcomes independent of treatment. diabetesjournals.org/care/article/d…

GRADE Trial

Weight gain  associated with worse glycaemic control & increased risk of cardiovascular and kidney outcomes  independent of treatment.

diabetesjournals.org/care/article/d…
GoggleDocs (@goggledocs) 's Twitter Profile Photo

📢 Can LFTs track liver fat loss after weight loss in #T2D? Yes. 🔹 DiRECT sub-study: 74% achieved MASLD remission with ~12kg weight loss 🔸 ⤵️ ALT & GGT = strong predictors of liver fat ⤵️ (ALT >40 = PPV 100%) 🔹 ALT change most closely linked to liver fat ⤵️ 🔸 LFTs =

📢 Can LFTs track liver fat loss after weight loss in #T2D? Yes.

🔹 DiRECT sub-study: 74% achieved MASLD remission with ~12kg weight loss

🔸 ⤵️ ALT & GGT = strong predictors of liver fat ⤵️ (ALT >40 = PPV 100%)

🔹 ALT change most closely linked to liver fat ⤵️

🔸 LFTs =
Dominika Antoniszczak (@dominikadds) 's Twitter Profile Photo

Living with #Diabetes? Want to know how to prepare for your next dental appointment? 🦷🪥📆 Check out our dental guide for #PwD at the Perio-Diabetes Hub Hub. Made with care. Backed by expertise. Shaped by lived experience. periodiabetes.org/wp-content/upl… #gbdoc #DMOralHealth #DOC

Living with #Diabetes? 

Want to know how to prepare for your next dental appointment? 🦷🪥📆

Check out our dental guide for #PwD at the <a href="/PerioDiabetes/">Perio-Diabetes Hub</a> Hub. 

Made with care.
Backed by expertise.
Shaped by lived experience.

periodiabetes.org/wp-content/upl…

#gbdoc #DMOralHealth #DOC
Dr Amar Puttanna 🎸 (@amarput) 's Twitter Profile Photo

Glad to have worked on this in one of my areas of clinical interest - a comprehensive resource for both diabetes and dentistry! Special mention to those involved esp our dentist lead Dr Rattu 🙌🏽 Have a look! GoggleDocs Prof Kamlesh Khunti EDEN Diabetes Training ABCD Diabetes 📰Diabetes Times

Dominika Antoniszczak (@dominikadds) 's Twitter Profile Photo

So proud to see Dr. Zehra Yonel from Uni of Birmingham championing the role of dental teams in diabetes screening - showing how research translates into practice. A powerful and timely message at #EuroPerio11 🇦🇹 National Institute for Health and Care Research EFP #DMOralHealth #gbdoc

So proud to see Dr. <a href="/zehra_yonel/">Zehra Yonel</a> from <a href="/unibirmingham/">Uni of Birmingham</a> championing the role of dental teams in diabetes screening - showing how research translates into practice. A powerful and timely message at #EuroPerio11 🇦🇹

<a href="/NIHRresearch/">National Institute for Health and Care Research</a> <a href="/PerioEurope/">EFP</a> #DMOralHealth #gbdoc
The Lancet Diabetes & Endocrinology (@thelancetendo) 's Twitter Profile Photo

New—Mexico's junk food and soda taxes thelancet.com/journals/landi… #obesity #PublicHealth #FREE to read with registration (also FREE)

GoggleDocs (@goggledocs) 's Twitter Profile Photo

👵 CGM works for older adults—but they’re being left behind 🔹 17 studies, incl. 5 RCTs: strong evidence CGM reduces hypos 🔸 HbA1c unreliable in older age—TIR & TBR matter more 🔹 CGM cuts hospitalisations, distress, & improves QoL 🔸 Yet uptake remains lowest in 65+ 👉 Age

👵 CGM works for older adults—but they’re being left behind

🔹 17 studies, incl. 5 RCTs: strong evidence CGM reduces hypos

🔸 HbA1c unreliable in older age—TIR &amp; TBR matter more

🔹 CGM cuts hospitalisations, distress, &amp; improves QoL

🔸 Yet uptake remains lowest in 65+

👉 Age
Prof Kamlesh Khunti (@kamleshkhunti) 's Twitter Profile Photo

34 year follow-up of Da Qing study 50% of Chinese adults with newly diagnosed diabetes and IGT experienced stroke. A reduced stroke risk was observed in the overall IGT intervention group diabetesjournals.org/care/article/d…

34 year follow-up of Da Qing study

50% of Chinese adults with newly diagnosed diabetes and IGT experienced stroke.

A reduced stroke risk was observed in the overall IGT intervention group

diabetesjournals.org/care/article/d…
Prof Kamlesh Khunti (@kamleshkhunti) 's Twitter Profile Photo

GLP1-RA therapy with liraglutide or semaglutide for 12 months is efficacious and safe for the treatment of weight regain following bariatric surgery. But what about the longer term?? link.springer.com/article/10.118…

GLP1-RA therapy with liraglutide or semaglutide for 12 months is efficacious and safe for the treatment of weight regain following bariatric surgery.

But what about the longer term?? 

link.springer.com/article/10.118…
Dr Amar Puttanna 🎸 (@amarput) 's Twitter Profile Photo

Absolute pleasure to talk on complications and also oral health in diabetes! Spreading the knowledge … also managed to get some mentorship advice from a diabetes queen 😁 Thank you Diabetes Ireland Kate Gajewska Prof Kamlesh Khunti

Absolute pleasure to talk on complications and also oral health in diabetes! Spreading the knowledge … also managed to get some mentorship advice from a diabetes queen 😁 Thank you <a href="/Diabetes_ie/">Diabetes Ireland</a> <a href="/kate_gajewska/">Kate Gajewska</a> <a href="/kamleshkhunti/">Prof Kamlesh Khunti</a>
GoggleDocs (@goggledocs) 's Twitter Profile Photo

🇨🇳 Mazdutide delivers in Chinese adults with obesity 🔹 Phase 3 RCT (n=610), 48 wks 🔸 Weight ↓ −14.0% (6mg), −11.0% (4mg) 🔹 50% hit ≥15% loss on 6mg vs 2% placebo 🔸 BP, lipids, liver fat & uric acid all improved 👉 Dual GLP-1/glucagon agonism is real-world ready

🇨🇳 Mazdutide delivers in Chinese adults with obesity

🔹 Phase 3 RCT (n=610), 48 wks

🔸 Weight ↓ −14.0% (6mg), −11.0% (4mg)

🔹 50% hit ≥15% loss on 6mg vs 2% placebo

🔸 BP, lipids, liver fat &amp; uric acid all improved

👉 Dual GLP-1/glucagon agonism is real-world ready
GoggleDocs (@goggledocs) 's Twitter Profile Photo

💦 Why taking the pee is important in MASLD too! 🔹 NHANES 2001–18: 3412 with MASLD 🔸 UACR >7.5 mg/g (even within ‘normal’) = ↑ death risk 🔹 Each 1 mg/g ↑ = +4% all-cause, +5% CV mortality 🔸 KM & spline curves confirm rising risk 👉 Check the kidneys—your liver

💦 Why taking the pee is important in MASLD too!

🔹 NHANES 2001–18: 3412 with MASLD

🔸 UACR &gt;7.5 mg/g (even within ‘normal’) = ↑ death risk

🔹 Each 1 mg/g ↑ = +4% all-cause, +5% CV mortality

🔸 KM &amp; spline curves confirm rising risk

👉 Check the kidneys—your liver
Prof Kamlesh Khunti (@kamleshkhunti) 's Twitter Profile Photo

Our paper on second-line treatment with SGLT2i in routine practice in T2 diabetes More effective than SU or DPP4i in reducing HbA1c Effective across ages, baseline HbA1c and presence of multiple long term conditions With London School of Hygiene & Tropical Medicine & Amanda I Adler link.springer.com/article/10.100…

Our paper on second-line treatment with SGLT2i in routine practice in T2 diabetes

More effective than SU or DPP4i in reducing HbA1c 

Effective across ages, baseline HbA1c and presence of multiple long term conditions

With <a href="/LSHTM/">London School of Hygiene & Tropical Medicine</a>  &amp; <a href="/DrAmandaAdler/">Amanda I Adler</a> 

link.springer.com/article/10.100…
GoggleDocs (@goggledocs) 's Twitter Profile Photo

💉 Bimagrumab: “BELIEVE or not to BELIEVE” — that is the question Weight loss without muscle loss? 🚨 New data coming #ADA2025 🚨 👉We will be there 🧠 Most obesity drugs ↓ fat and muscle — ↑ sarcopenia risk. 🔬 Bimagrumab (ActRII blocker): ↑ lean mass, ↓ fat mass. 📊

💉 Bimagrumab: “BELIEVE or not to BELIEVE” — that is the question
Weight loss without muscle loss?

🚨 New data coming #ADA2025 🚨 
👉We will be there

🧠 Most obesity drugs ↓ fat and muscle — ↑ sarcopenia risk.

🔬 Bimagrumab (ActRII blocker):
↑ lean mass, ↓ fat mass.

📊