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Led by the Susruta Majumdar , we worked with labs of Ron Dror, Kaavya Krishna Kumar, Michael Cameron, Amynah Pradhan and Brian Kobilka to develop a next-generation cannabinoid CB1 agonist

Estradiol protects against pain-facilitated fentanyl use via suppression of opioid-evoked dopamine activity in males - ScienceDirect. New lab work published in ⁦Neuron⁩! sciencedirect.com/science/articl…

Female sex hormone protects against opioid misuse, rat study finds – WashU Medicine. And here is WashU ⁦WashU Office of Neuroscience Research⁩ ⁦WashU Medicine Neuroscience⁩ press release! medicine.washu.edu/news/female-se…

Please join us in congratulating Dr. Abraham! Her leadership in health informatics will drive innovation in patient-centered care and safety at WashU Medicine.

In this brief communication, authors share a case of a patient admitted for EEG monitoring whose intracranial recording captured #corticalspreadingdepression during an attack of #migraine with #aura …adachejournal.onlinelibrary.wiley.com/doi/full/10.11… Graham A. McLeod MD, Samuel Wiebe et al

Check out the new preprint from the lab demonstrating that the posterior thalamus is necessary for some migraine-like behaviors! Great work by our team! Especially my graduate student Agatha Greenway biorxiv.org/content/10.110…

Join us for the @ClinicPharmSTL Research Seminar featuring Lauren Slosky from UMN Pharmacology and MPaT. Details ⬇️ 📆 Thursday, March 13 ⏰ 1-2 p.m. 📍 UHSP Academic and Research Building room 449 anesthesiology.wustl.edu/events/event/c…

Interested in non-addictive analgesics to address chronic pain without the risk of opioid overdose deaths? A new selective δ opioid receptor (δOR) partial agonist called C6-Quino, with differential activity at G-protein and arrestin pathways, decreases multiple types of pain

The Center for Clinical Pharmacology is such an amazingly collaborative place! Such a treat to work with so many good people! WashU Medicine Anesthesiology Research University of Health Sciences and Pharmacy in STL

Cannabinoid targets hidden pocket for safer pain relief nature.com/articles/d4157… Highlight of our cannabinoid paper by Nature reviews drug discovery Rob Gereau Vipin Rangari Dror Lab Amynah Pradhan Rich Slivicki Center for Clinical Pharmacology Evan O’Brien WashU Medicine WashU Medicine Anesthesiology Research

Last weekend, women from #WashUanesthesiology gathered for the 3rd annual WoW Retreat! A day of connection, creativity, and reflection—with workshops, yoga, sound healing, and more. Read the highlights: anesthesiology.wustl.edu/highlights-fro…

This new paper from the team shows that MAGL inhibitor is effective in a migraine model and doesn’t cause tolerance. Also in situ showing wide distribution of MAGL and CB1 in neuronal and non-neuronal cells in TG and TNC.

Congratulations to six #WashUanesthesiology faculty honored with the 2025 Dean’s Impact Award from @WashUmedicine for their extraordinary impact across clinical care, research, and education through community-focused work. anesthesiology.wustl.edu/six-department…

Join us at the American Headache Society annual scientific meeting in June 2025 in Minneapolis for the latest #headache research! #AHSAM

Congratulations to Eric Kaiser for winning the Early Career Award #AHSAM

Last one for the day - Congratulations to current Pradhan lab postdoc Yaseen Awad Igbaria and future postdoc Ya Yu Hu for winning this year’s Frontiers in Headache Research Scholarship #AHSAM 🎉