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Subclinical primary aldosteronism + Natriuretic Peptide Insufficiency => HYPERTENSION academic.oup.com/jcem/advance-a…

Primary aldosteronism

Do patients want to be screened for primary aldosteronism: Yes How much PA can be identified with a direct-to-patient approach: A Lot Can this approach be implemented nationwide: Yes Jen Brown ahajournals.org/doi/10.1161/HY…

Work smarter, not harder! A low renin with concurrent use of ACEi/ARB is almost certainly some shade of Primary Aldosteronism. Either way, aldosterone-directed therapy is very likely to provide major clinical benefits ahajournals.org/eprint/TUS6CGX… Cheng-Hsuan Tsai

More evidence for treating hypertension with mineralocorticoid receptor antagonists, if renin is low despite ACE-inhibition. It is probably #PrimaryAldosteronism!

Now online in Cancer Discovery: Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes - by Carlota Arenillas, ToledoLab_VHIO, and colleagues doi.org/10.1158/2159-8… Vall d’Hebron Institute of Oncology (VHIO)

Clever and beautiful study

Findings from a new study suggest a significant paradigm shift in the field of hypertension. Researchers from UCalgaryMedicine say confirmatory testing for primary aldosteronism, a common cause of #hypertension, often misinforms care and should be removed from the diagnostic care

Beautiful study by Alex Leung, MD MPH et al. Hopefully this will keep the momentum going for simplifying PA diagnosis and or empiric MR antagonist thearpy. acpjournals.org/doi/10.7326/AN…

Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug discovery. Learn more in the Review Article “Chemical Complexity of Food and

A new interactive feature describes a 68-year-old woman who presented to the ED with dizziness and shortness of breath on exertion that abated with the use of an albuterol inhaler. She reported a 4-day history of cough, sore throat, and nasal congestion. Test your diagnostic and

A 68-year-old woman presented to the emergency department with dizziness and shortness of breath with exertion. On the day of presentation, she had been playing pickleball when she felt her airway closing and began to have cough, shortness of breath, and dizziness. Her

ahajournals.org/doi/10.1161/HY…

Low-renin hypertension despite the use of ACE inhibitors or ARBs is almost certainly a form of primary aldosteronism. Thrilled to know that our group's work is the featured article in this month's issue of hypertension ! ahajournals.org/doi/full/10.11… Anand Vaidya Jen Brown

Serum proteomic signatures raise new possibilities for distinguishing primary aldosteronism from essential hypertension! Our latest study is now published in the European Journal of Clinical Investigation! onlinelibrary.wiley.com/doi/10.1111/ec… Anand Vaidya European Journal of Clinical Investigation

RESEARCH ARTICLE: ACE Inhibition to Distinguish Low-Renin Hypertension From Primary Aldosteronism ahajrnls.org/4jHn0Qb

Adrenal Insufficiency

More Adrenal Insufficieny

A pragmatic approach to evaluate for ADRENAL INSUFFICIENCY Thanks to Irina Bancos and Jay Findling for sharing their expertise!

The Impact of Modern Industrialized Dietary Sodium Intake on the Plasma Proteome academic.oup.com/ajh/advance-ar…