"This study reveals that the SPC, discovered in the 1970s to cleave ER signal peptides, has a previously unanticipated and widespread quality control function for membrane proteins." Cool story from @lemberg_lab & @cpblab. See thread below ⬇️

New function of the signal peptidase complex discovered: The @cpblab @TU_Muenschen and @lemberg_lab #UniCologne have shown that it performs quality control of membrane proteins✅ 📰 Publication in Science Magazine ➡uni.koeln/GCP93

Congratulations to the @lemberg_lab Biochemistry Center Cologne Uniklinik Köln Universität zu Köln + collaborators for their publication Science Magazine 🎉🍾 portal.uni-koeln.de/en/universitae…

Important piece of work about yet another function of the signal peptidase complex. Congratulations to @lemberg_lab , now in Cologne, and @cpblab!

The human signal peptidase complex acts as a quality control enzyme for membrane proteins | Science science.org/doi/10.1126/sc…

🤯🤯🤯 So much beautiful work in this paper! Great work @lemberg_lab @cpblab!

Today we're showcasing Alessandra in our #MPIMRSpotlight. 🌠👩‍🔬 Alessandra joined the Biophysical Engineering group as a PostDoc last year. Alessandra Griffo

Our manuscript describing the structures of connexin 32 (Cx32) gap junction channel and hemichannel is now out on bioRxiv. biorxiv.org/content/10.110…

Mind blowing discovery from Björn Schumacher lab: The DREAM complex transcriptionally represses essentially all DNA-repair systems and thus operates as a highly conserved master regulator of the somatic limitation of DNA-repair capacities. DREAM mutants repair DNA better in the soma

Italian Universities must increase the salary of PhD students to be attractive. However, they don't care, perhaps because they assume that they can always hire internal candidates who are happy with a tiny stipend. They don't really give a damn about international competitiveness

(1/2) Meet our Horizons speaker Dr. Marius Lemberg! @Marius_Lemberg @lemberg_lab Dr. Lemberg is a Professor for Biochemistry at the Biochemistry Center of the Medical Faculty of Cologne University, Cologne, Germany Universität zu Köln.

ERC Starting Grant for DKFZ researcher Angelika Feldmann: she wants to explore the molecular processes that are required during the development of an organism so that all cells can read the right genes at the right time. European Research Council (ERC) ➡️ t1p.de/5zm8j

🔬🧬 Cologne researchers @lemberg_lab Biochemistry Center Cologne CECAD Cologne have discovered a new regulatory mechanism that keeps the immune system in check! The intramembrane protease RHBDL4 prevents the immune system from overreacting. Read more 👇 uni.koeln/ZNHFQ

You need a proteins, but a few only and delivered in a non-invasive manner? For single molecule imaging maybe? Or to reconstitute functioning a knockout? Purba Kashyap has the solution! So excited to see it out. Constructs soon on Addgene nature.com/articles/s4159…

Applications *only* through the Cologne Graduate School of Ageing Research website: application.ageing-grad-school.de/site/index.php. Deadline Nov. 4th, 2024. Starting date: summer 2025. Please share and retweet!

One of the main reasons I moved to Germany was for its strong biophysics community. Receiving the Young Investigator Award at #DGfB2024 is a true honor, and I’m excited to contribute to the German biophysical society. Thank you all for this recognition! 🇩🇪🔬🏆🎉🎉

Habemus Logo! – we have our official Lipid logo! Huge thanks to Ella Marushchenko for the amazing design! #lipidtime

The first paper of my PhD is finally out! 🎉 That comes after years of effort, and I’m happy that I shared this with one of my closest friends @DAngelidaki! Thanks to Costas for the support and mentorship, and all co-authors for the help, especially Julian Nüchel (PhD) and Jiyoung Pan!