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Very excited to propose a new idea in the context of epigenetic inheritance - "Diffusion Accessible Domains" or DADs, in the first manuscript from our new lab at National Centre for Biological Sciences and Living Machines-NCBS. A big shoutout to Archit Singh for all the hard work! Thread to follow soon.

Can we combine inhibitors of the #circadian clock and lineage correlations to detect presence of cell cycle gating by the clock? Excited about our new manuscript from National Centre for Biological Sciences, Living Machines-NCBS showing how this might be possible! A short thread (1/6) tinyurl.com/46pub9rh

Is it always possible to assign #GeneExpression #CellStates to #SingleCells? Or can biological noise set fundamental limits? In our new work, we show that #CircadianClock states *cannot* be assigned to single cells due to transcriptional noise! tinyurl.com/4uxdxw2k (1/8)

Inheritable 'memory' genes drive #cancer drug tolerance, but their discovery in clinical samples is a major challenge. Our new theory, moving away from Luria-Delbruck, detects them from a *single* scRNA-seq dataset! With #ArchishmanRaju led by Suvranil tinyurl.com/4pef8scy