🚨 Can We Avoid Surgery in Esophageal Cancer? The SANO Trial Has Answers! 🚨OncoAlert A new ph 3 trial suggests that active surveillance after neoadjuvant chemoradiotherapy (CRT) may be a safe alternative to immediate surgery. Let’s break it down! 🧵⬇️

Just published in Journal of Clinical Oncology the updated ASCO guidelines on fertility preservation in people with #cancer: a must read for all colleagues involved in cancer care to increase awareness on #oncofertility issues OncoAlert Ann Partridge MD, MPH Oncofertility Link: ascopubs.org/doi/10.1200/JC…

This paper is a must-read. Almost certainly the best review of NPC you will read this year!! Many thanks to Melvin LK CHUA | FRCR, PhD, FASCO and colleagues for this contribution.

The NRG Health Care Access Committee will be hosting their annual symposium: “Conquering the Geospatial Divide Challenging Rural Research & Cancer Care Delivery: Real world discussions with rural providers, trialists, & patient caregivers." Learn more: ow.ly/4JlJ50Vij20

❗️ CRT + 3-4 doses of sotigalimab (CD40) in esophageal cancer A whopping pCR of 60% in SCC Wow 🤩 great regimen for organ preservation pubmed.ncbi.nlm.nih.gov/39907035/

Here is HCC 101 video! ~30 min covering imaging, HCC management overview, approach to deciding b/w local therapies. This video was a little longer, so I put in some pics from recent trip to India to keep folks awake 😀. Full video link & slides in replies. 1/8

🚀Ph2 SMART ONE trial in press 🔹1-fx SBRT on 0.35T MR-Linac 🔹2/3 targets abd/pelvis, 1/3 lung 🔹🔥🔥 plans!! Median GTV mean dose: adrenal 32.3 Gy, LN 31.7 Gy, liver 45.4 Gy, lung 42.8 Gy 🔹Median time 53 min, ART routine 🔹1-yr LC 96.2%, 1-yr OS 86.3% redjournal.org/article/S0360-…

Check out the latest recommendations for contouring low-grade gliomas – with practical insights on volumes, OARs, and imaging integration. A must-read for clinical practice and planning optimization. #RadOnc #NeuroOncology #Contouring #RTplanning ⬇️⬇️⬇️ thegreenjournal.com/article/S0167-…

“There is a biological basis for why immunotherapy before fractionated radiotherapy rather than concurrent may be the optimal approach”. Aditya Juloori ascopubs.org/doi/10.1200/JC…

Epic #ARS2025. Thanks to Amer. Radium Society for hosting a fantastic meeting. Til next time!

Congrats to Alden D'Souza Kylie Kang for this work on MR guided adaptive SBRT for pancreatic tumors abutting/invading organs at risk in IJROBP - The Red Journal. Classic teaching is to prolong fractionation and avoid SBRT for OAR abutment/invasion due to toxicity. Still true in ART era? 1/

Nice commentary by William A Hall, MD et al: jamanetwork.com/journals/jamao…

Anal Cancer 101 video! Treatment for anal cancer relatively straightforward for most, but several nuances (i.e. anal margin, etc) & trials coming down pipeline aiming to better tailor care to stage/biology. I review in this 17 min video. Full video link & slides below 🧵. 1/6

My GI Onc 101 series is done (for now). ~20-30 min videos on: rectal, esophagus/GEJ, pancreas, anal cancers, & HCC. All on my YouTube channel. I have a million more teaching video ideas, so subscribe for updates if you'd like (it's free 😀). Link to channel below in replies.

🚨CAO/ARO/AIO-12 + OPRA Rectal trials🚨 WW vs. Planned surgery after TNT for rectal Ca 🟰 OS, DFS, DM ‼️Comparable outcomes when matched for response (cCR vs. pCR, etc) 🙌Supports WW as a highly appropriate, pt-centric, option for patients with cCR after TNT

🎧📻To all my GI peeps, take a listen to the latest NRG Oncology podcast episode featuring Karyn Goodman, MD, MS and Ross Abrams if you want to hear a great take on history of pancreas cancer research and all things #RTOG0848 👉🏼Spotify: ow.ly/IjOh50VHVCo 👉🏼🍎: ow.ly/5PQm50VHVCs

Radiation Oncology is an alphabet soup of terminology! What does SBRT/SAbR mean? IMRT? Proton? Learn how we categorize our radiotherapy treatments in this 3 minute video clip.

Does radiotherapy have a role in patients with unresectable or medically inoperable gastric cancer? Love the design of GastroSCOPE: a 3-part risk-adapted RCT assessing +/- RT across 3 patient groups. Look forward to seeing results in coming years. #ESTRO25

I’m SO delighted to finally see the STAR-TREC data reported 🤩 #ESTRO25 Short course RT vs chemorad for organ preservation in early stage rectal cancer 61% vs 80% TME-free survival at 12 months ➡️ More organ preservation with long-course chemorad! #radonc #rectalcancer

Huge congrats to David Sebag (he/him) 🇺🇦💙 & team! PLATO ACT 4 - randomized data supporting use of reduced dose RT for early stage anal cancer. The recently completed DECREASE trial will provide more data on this. In the meantime, very reasonable to start adopting reduced dose RT as SOC