Very happy to report that our paper is out in Nature Communications! 🥳 We found that assembly and disassembly of p16 amyloid fibrils is fully controlled by a redox reaction. Thanks to Sarah Heath, Christoph Göbl and co-authors for this team work! nature.com/articles/s4146…

Ca2+-driven PDIA6 phase separation to ensure proinsulin quality control dlvr.it/TBHFyw

Happy Hive Honey Chocolates, founded by University of Michigan Medical School professor Brian Stork, has sold honey chocolates that have netted over $10,000 in proceeds for Step Up, a nonprofit that helps unsupported young adults with stable housing. myumi.ch/8rkqk

Update: I've joined ETSU Biological Sciences as an Assistant Professor. I'm thrilled to continue my research on #proteinfolding in #diabetes. Here's my recent science talk that offers an overview of my current research focus. Thanks to the(sugar)science youtu.be/EM0QzHe82IU?si…

I am thrilled to announce that I will be opening my own lab in Oct 2024 at City of Hope. The Baumel-Alterzon lab will explore the importance of redox regulation in beta-cell life. We're looking to recruit passionate scientists at all levels—stay tuned for more info.

Excited to share our new paper with Sebastian Kmiecik lab! Dive into the details and possibilities of Aggrescan4D, the latest A3D update featuring pH-dependent #protein #aggregation prediction! Now in Protein Science! proteinsociety Universitat Autònoma de Barcelona Institut de Biotecnologia i de Biomedicina UAB Institut d'Investigació i Innovació Parc Taulí onlinelibrary.wiley.com/doi/full/10.10…

🔎 Scientists from WashU Medicine identified crinophagic granules, a minor set of vesicles formed by fusing lysosomes with the conventional insulin dense-core granules, to be pathogenic in type 1 #diabetes development in mouse models. Nature Communications go.nature.com/4dKS66J

The Martin lab an open postdoctoral position at the interface of #cytoskeleton and #condensate biology, in a fantastic research community UNIGE_en Biologie - UNIGE Molecular & Cellular Biology Dept 🔬 Geneva 🇨🇭 LifeSciencesPhD_UNIGE If interested, do not hesitate to contact us: mocel.unige.ch/research-group… Please RT!

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

Identification of novel type 1 and type 2 diabetes genes by co-localization of human islet eQTL and GWAS variants with colocRedRibbon #geneticvariants #gwas #diabetes medrxiv.org/content/10.110…

Now Online: Homeostasis control in health and disease by the unfolded protein response go.nature.com/4hxWDMJ

In eLife - the journal: Cancers adapt to their mutational load by buffering protein misfolding stress doi.org/10.7554/eLife.…

New in JBC press: "Chaperone mediated disaggregation of infectious prions releases particles that seed new prion formation in a strain specific manner." Learn more: jbc.org/article/S0021-…

Our first article from ETSU. 🙂Thanks to all the undergrads in my lab and Srivastav Ranganathan! Exploring proinsulin proteostasis: insights into beta cell health and diabetes Frontiers - Molecular Biology #proinsulin #proteinfolding #ERqualitycontrol #diabetes Link: frontiersin.org/journals/molec…

Scott Soleimanpour Scott Soleimanpour a member of Caswell Diabetes Institute, discusses the science of diabetes, blending personal insights and cutting-edge research that gets into mitochondrial biology. Check out his episode on the podcast Mind & Matter: michmed.org/DQY8B.

🔊New article: The B22 Dilemma: Structural Basis for Conformational Differences in Proinsulin B-Chain Arg22 Mutants mdpi.com/3267264 #mdpibiomolecules via Biomolecules MDPI with Srivastav Ranganathan ETSU #proteinfolding #moleculardynamics #diabetes

Still accepting manuscript submissions. Please reach out to me if interested.

We are hiring! I am recruiting a postdoctoral fellow to join us studying cell stress responses and organelle communication in pancreatic beta cells. Cell and molecular biology background is highly desired. Interested? please contact me at [email protected]. hr.wisc.edu/postdoc-and-re…