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@Absteward has reported that BALANCE is now published, so the Table is now updated! GNB bacteremia is now listed as Bacteremia (non S. aureus). Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia. bradspellberg.com/shorter-is-bet…

Antibiotic prophylaxis for SBP in cirrhosis has been standard of care since the 1990s—but is the evidence strong enough to support it? Time to rethink this practice! Excellent commentary by Dan Markley Jasmohan Bajaj Clinical Infectious Diseases #IDXposts #ASEPTICRCT academic.oup.com/cid/article/do…

Oh no, the pipeline is dying! Uh...nevermind. 🙄 academic.oup.com/healthaffairss…

Oh no! The pipeline is still not dying! We're not even half way through the current 5 year period in the graph... Also, the Table is getting awfully full!

Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 Ooh good catch. It's in the graph. There was a version control issue with the table. See it updated here.

Still some scepticism in the audience about #phage therapy at #ESCMIDGlobal2025 BSAC UKCPA Infection Committee @biainfection UK Health Security Agency

SNAP/COLCEBA trial session starting now Steven Tong Joshua Davis Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 Staph aureus causes 1 million deaths per year worldwide. Less than 4.5k randomized in staph aureus bacteremia. Randomized care is better than random care. SNAP platform started on a napkin. #ESCMIDGlobal

Big trial for this question (n=1,341). Median age of 66, 2/3 had at least one comorbidity, low IVDU, 10% in ICU, but 12% immunocompromised. Most sources are skin and bone. Less than 1% CNS infection. #ESCMIDGlobal2025

17% vs 15% mortality, non inferior, at 90 days. Kaplan Meir and differences in mortality at other time points are below. Big difference in AKI 19.1 vs 13.7 %. Flucox vs cefazolin.

Incidence of Allergic Reactions to Cefazolin in Patients with Penicillin Allergy Undergoing... - goo.gl/scholar/HKRwLC #ScholarAlerts

Complicated UTI. Glad that I’m not the only one confused on the definition. #ESCMIDGlobal2025

#IDTwitter #IDXpost should we start talking about Subcutaneous administration of antibiotics vs IV vs PO? academic.oup.com/jac/article/80… Brad Spellberg Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 Todd C. Lee Steven Tong Jonathan Ryder, MD Alice Han Nico Cortes-Penfield MD FACP FIDSA 🦴💊 William Wright too soon?

Sepsis alert in the ED 🚨 Overuse of antibiotics and aggressive regimens are sparking complications. See the alarming stats below! How can we boost antibiotic stewardship in ED ? Share your thoughts! [Link to the new study in CID] academic.oup.com/cid/advance-ar…

Chickenpox is now a notifiable disease. Treatment and management protocols remain unchanged: bit.ly/4lNjvKq

Disappointing, again. Tigecycline linked to pancreatitis—yet still being recommended when safer antibiotic alternatives are available. Stewardship means choosing wisely and putting patient safety first What unforgettable AE have you encountered with tige? academic.oup.com/jac/article-ab…