Check out our preprint on redox-coupled sodium pumping of the ancient Rnf machinery. Great collaboration with SchullerJM and Müller Labs. doi.org/10.1101/2024.0…

Molecular principles of redox-coupled sodium pumping of the ancient Rnf machinery | bioRxiv biorxiv.org/content/10.110…

Our recent findings that the Fe #nitrogenase reduces #CO2 under physiological conditions are now out in Science Advances. doi.org/10.1126/sciadv… Great work by @NielsOehlmann and Frederik Schmidt

Great work by @BisLightyear

Excited to share our latest research on co-translational mRNA decay by the exosome in human cells! We uncover how the exosome-SKI complex is recruited to ribosomes and propose a novel role for SKI in recognizing collided disomes. Max Planck Institute of Biochemistry (MPIB) 👇👇👇

Moreover, we will explore the role of [FeFe]-hydrogenase in multienzyme complexes, e.g., driving CO2 and CO reduction via H2 oxidation and electron bifurcation.

I will be hiring officially later this year, but if you are interested in pursuing a Phd focused on metalloenzymes and infrared spectroscopy... Give me call!

Our latest work on a #nitrogenase-like enzyme, the methylthio-alkane reductase which surprisingly also contains large nitrogenase metalloclusters, the P-cluster and the [Fe8S9C]- (L)-cluster is now online: doi.org/10.1101/2024.1… Have a look at the 🧵 by @AnaLagoMaciel.

Great work from my colleague Tomas Pascoa

Two exciting papers about the the protection of nitrogenases from O2 by the ferredoxin Shethna protein II from the Tezcan doi.org/10.1038/s41586… and Einsle doi.org/10.1038/s41586… labs were published today by nature. Surprisingly both papers reveal superstructures of filaments.

Very proud to share our latest work on the ancient the Na+-pumping Rnf complex – now out in Nature Comms. Thank you Schuller & Müller Labs for great collaboration, and KAW for generous funding nature.com/articles/s4146…

Excited to share our latest work on the structure and mechanism of the ancient sodium-pumping Rnf complex, now out in Nature Communications nature.com/articles/s4146…

Take a moment to check the most recent publication by Anuj Kumar et al., about the structure & mechanism of a major respiratory complex in anaerobes 👇🏼

I'm truly excited to announce our new publication in nature unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to Anuj Kumar for the fantastic illustration! LINK: nature.com/articles/s4158…

Check out this fantastic thread from Fidel Ramírez about out latest work out in Nature!! 🥳🥳

This is a wild paper. The anaerobic biochemistry is definitely worth your while (and beyond me to explain), but let me try to explain why this is also an evolutionary bombshell. This is about how nitrogen fixation evolved as we know it.

Nature research paper: Structure of the ATP-driven methyl-coenzyme M reductase activation complex go.nature.com/3Esgnmi