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Neurovascular complications in antiphospholipid syndrome, including stroke, cerebral venous thrombosis, and cognitive impairment, pose management challenges. This review covers evidence on mechanisms, anticoagulation, and research gaps. fcj9.short.gy/KMo2xE

Study identifies potential associations between 5,10-methylenetetrahydrofolate reductase (MTHFR C677T) and interleukin 4 (IL-4 I3VNTR) gene polymorphisms and distal symmetrical polyneuropathy (DSP) in children and adolescents with type 1 diabetes. fcj9.short.gy/crR9Vx

Vestibular disorders update: Research on peripheral vestibular hypofunction confirms the value of rehab exercises and suggests proprioceptive methods may outperform standard approaches. fcj9.short.gy/U36QIg

Research on migraine uncovers the association of the IL1A -889C > T (rs1800587) variant with aura and osmophobia. #Migraine #Aura #Osmophobia #IL1A #SNP #Neurology fcj9.short.gy/Ty7PbB

Since anti-NMDA receptor encephalitis (2007), 12+ autoimmune encephalitis syndromes emerged. Advances in HLA links, diagnostics, and phenotypes are reshaping care, with insights into late-onset cases, tumor links, and pediatric criteria. Learn more: fcj9.short.gy/CGv7mK

Heart rate variability (HRV) in chronic ischemic stroke patients shows reduced vagal activity and imbalance in sympathetic/parasympathetic systems, especially during sleep. These imbalances could persist for months post-injury. Read more: fcj9.short.gy/vyNBHp

New work highlights alexithymia as a new accessory symptom of cluster headaches. #ClusterHeadaches #Alexithymia #LymbicSystem #Neurology" fcj9.short.gy/xE2WS7

Listen to this: Patients with Parkinson’s have higher hearing thresholds at high frequencies. Brainstem responses are normal, but cortical auditory potentials show reduced amplitudes, indicating deficits in automatic and attentional processing. fcj9.short.gy/noljqP

Pioneers of neurology in Japan! Kawahara described progressive bulbar palsy and wrote the first neurology textbook. Miura studied ALS and co-founded the Japanese Society of Neurology. European influence, especially from Charcot and Bälz, was key. 🔗 fcj9.short.gy/2JWiHS

Alzheimer’s, vascular dementia, and diabetic cognitive impairment are linked to lipid metabolism disorders. Altered lipids impact Aβ, tau, and insulin resistance, worsening neurodegeneration. APOE, crucial in lipid transport, is a key treatment target. fcj9.short.gy/Wd0NWK

Don’t blink twice! A 14-year study of 151 patients w/Hemifacial spasm treated with botulinum toxin showed an initial dose increase over 3.46 years, then stabilization. Side effects were temporary, with weakness (17.9%) and ptosis (3.3%). fcj9.short.gy/N71oR3

Dual antiplatelet therapy (DAPT) vs. single (SAPT) in non-minor ischemic stroke (NIHSS ≥ 4): meta-analysis of 12,480 patients found no significant difference in recurrence, bleeding, or mortality. fcj9.short.gy/7p3ihF

🔬 A new frontier in neurology: it's not just roots, nerves, or plexuses anymore. Autoantibodies now target microtopographic zones — reshaping how we diagnose and treat neuropathies. Precision is going microscopic. #NeuroImmunology #Neurology fcj9.short.gy/lG8zKN

Brain magnetic resonance imaging showed a T2/fluidattenuated inversion recovery brainstem lesion at the dorsal pontomesencephalic junction (white arrows) with contrast enhancement (yellow arrows). Read more: fcj9.short.gy/cvbkqg

In low-income patients with temporal lobe epilepsy, QOL is shaped by more than seizures. Memory issues, anxiety, and depression worsen it—while social support, self-esteem, and cognition improve it. Holistic care matters. fcj9.short.gy/Pi4O5l

🔎 In refractory occipital neuralgia, ultrasound-guided CRFA of the proximal greater occipital nerve led to lasting pain relief in most patients—66% maintained >50% pain reduction at 1 year. Attack frequency & pain type predicted outcomes. Read more: fcj9.short.gy/FQiDRo

Professor Horácio Canelas played a key role in Wilson’s disease research in Brazil. His work at USP’s Neurologic Clinic put the country on the international map, making it a leading center in neurodegenerative diseases with metal accumulation. fcj9.short.gy/j8ve8n

🧠💬Donanemab, recently approved worldwide, was authorized by ANVISA on April 17. Experts discuss PROS, CONS, and future use of this anti-amyloid therapy for Alzheimer’s in Brazil. ✅ fcj9.short.gy/xZQycs ❌ fcj9.short.gy/5tWu06 ⚖️ fcj9.short.gy/O92ebO

NMOSD is more prevalent in Brazil, but limited access to AQP4-IgG testing delays diagnosis and care. Experts urge national guidelines, physician education, and expanded testing access to improve outcomes and reduce relapses. Read more: fcj9.short.gy/b4pLxs

Status epilepticus (SE) is a neuro emergency: “Time is brain.” For convulsive SE, treat after 5 min (T1); damage starts at 30 min (T2). Give IV benzos, then IV ASMs (phenytoin/levetiracetam in 🇧🇷). Refractory SE may require anesthetic coma. 🔗 fcj9.short.gy/TWVPNI