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Excited to share a new paper from my PhD work along with Shane O'Carroll from the Luke O'Neill lab on how the metabolite itaconate regulates IFN, out today in Nature Metabolism (nature.com/articles/s4225…) (1/n)

The Galván Peña lab is hiring! I’m looking for a research assistant to help me manage the lab and get our exciting projects on gut-systems communication off the ground. ummsjobs.com/job/10692/

Interferon lambda represent. Awesome session at #cytokines2024 ICIS 🦋 @cytokinesociety.bsky.social Amazing work presented by Achille Broggi Ivan Zanoni Steeve Boulant Tim Nice Rune Hartmann. Always so great to see what’s happening in the interferon world.

#EveryCellIsAnImmuneCell!💥Thrilled💥for our new paper Cell with Achille Broggi! We show that, during #IBD, type III #interferons delay gut repair by inducing #pyroptosis in intestinal epithelial cells via #gasdermin C upon ZBP1 activation! 1/n authors.elsevier.com/a/1k2OAL7PXqSL5

🎉💥Thrilled to share our latest research, now published in Cell, from Boston Children's & Harvard Medical School, carried out in Ivan Zanoni's Lab. authors.elsevier.com/a/1k2OAL7PXqSL5

Not to pick favorites – but IFNλ (and too much of a good thing!) in repairing the inflamed gut – a few fab colleagues/lab-mates/friends – and mentors – make for some really cool science. Congrats Achille Broggi Kautilya Kumar Jena Daniel Böhmer Benedetta Sposito et al & the boss, Ivan Zanoni 🧵👇

I am thrilled to announce that the Cancer Research Institute has awarded me a 3-year post-doctoral fellowship to study novel immunotherapies in pancreatic cancer in the laboratory of Ivan Zanoni at Boston Children's Harvard Medical School (1/3)

#LocationLocationLocation! Andrew Harrison Duomeng Yang Wang &co show Nature Immunology that in homeostasis GLUT4 is trapped in the Golgi, but upon virus encounter it relocates to the plasma membrane where it segregates & prevents signaling of RIG-I-like receptors! doi.org/10.1038/s41590…

I often say that tissue repair and tumorogenesis are two faces of the same coin. Ejv &co now show that this is not always the case and the two processes can be "unlinked" in the gut! nature nature.com/articles/s4158…

Feel so lucky to be working with an amazing group of passionate, talented, kind, and smart scientists that makes me better every day! #ZanoniLabHolidayParty #LoveMyJob #LoveMyLab #LoveScience (lot of #love during the Holiday time 😉)!

#EveryCellIsAnImmuneCell!💥Thrilled for the final version of our paper Cell! We show that type III #interferons control ZBP1 & Z-nucleic acid sensing driving gasdermin C cleavage & #pyroptosis of intestinal epithelial cells, delaying gut repair! cell.com/cell/abstract/…

The zanonilab.com just turned 10-year-old today! 🎂🎉 I feel so grateful to my mentors & all the amazing friends & trainees that shared these years of passion, excitement, & hard work! In our job, every day is a new start, but let’s celebrate some of our achievements 1/

#JoinUs! Today 4pm, Modell Center, I’ll be giving the Harvard Medical School Harvard University #Immunology seminar, tons of unpublished data, all about how we sense & respond to microbial & host-derived inflammatory signals during infections & sterile inflammatory diseases!

Honored to be part of this vibrant community! Cancer Research Institute Boston Children's Harvard Medical School #research #pancreaticcancer #immunology #immunotherapy

Congratulations to all especially Anukriti Mathur Department of Medicine UMass Chan Medical School

Our latest review explores the roles of neutrophils in metabolic syndrome—our first effort in examining their function and connection to metabolic conditions. Read more here hLife 👇👇👇 tinyurl.com/3v7jpenn

Must read for #InterferonLovers, and more! 👇👉 febs.onlinelibrary.wiley.com/doi/10.1111/fe…

#NoTimeToDie! Lien Kate Fitzgerald &co show PNASNews that Raver1 controls the splicing of RIPK1, impacting caspase-8, gasdermin D & E cleavage, & IL1 & IL18 activation, & pyroptic cell death in the context of Yersinia infection in vivo #ScienceSavesLives doi.org/10.1073/pnas.2…

#EveryCellIsAnImmuneCell! Andreas Wack & friends The Francis Crick Institute discuss Annual Reviews Immunology the crosstalk between immune & (so called 😉) non-immune cells in #lung during inflammation, damage & repair! #MustRead doi.org/10.1146/annure…