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CellMarker 2.0 An updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data http://117.50.127.228/CellMarker/index.html A nice resource for cell type markers for supervised clustering😁 Nucleic Acids Res 2023 academic.oup.com/nar/article/51…

A foundation model of 10 million ECGs shows how much is encoded in these recordings that cardiologists would not be able to detect NEJM AI ai.nejm.org/doi/10.1056/AI…

Our paper on ovarian cancer #LGSC is out in Cancer Cell. Using deep visual proteomics #DVP and spatial transcriptomics, we mapped how non-invasive tumors become deadly ovarian disease, and found a promising new treatment combination. cell.com/cancer-cell/fu…

Single-cell & spatial omics: exploring hypothalamic heterogeneity Transcriptomics Metabolomics Proteomics A very rich resource of human mouse #Hypothalamus studies till 2024 (Table 1 & 2😁) Neural Regeneration Research-Journal 2025 journals.lww.com/nrronline/full…

Online Now: Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression dlvr.it/TLbW6y

Tahoe-100M Single-cell transcriptomic perturbation atlas🤠 ~100 M cells ~50 Cancer cell lines/spheroids (any normal cell for toxicity?😁) ~1100 small-molecule agents 52k cell-drug interactions Mosaic platform #OpenScience #VirtualCell Yusuf Roohani Arc Institute Johnny Yu

A “niche” study by David Lyden Weill Cornell Medicine in Cell (collaboration with Diane M. Simeone, MD): Extracellular vesicles from the lung “pro-thrombotic niche” (PTN) drive cancer-associated thrombosis and metastasis via integrin beta 2 cell.com/cell/abstract/…

Lung cancer survival more than doubles from 2000-2020 due to the collective efforts of precision medicine, immunotherapy, & early detection - 5015pts w lung adenocarcinoma🇫🇷 - mOS 8.5m (2000) v 20.7m (2020) ⁦OncoAlert⁩ #LCSM evidence.nejm.org/doi/full/10.10…

Did you catch the Queensland Spatial Biology Centre on Channel9? Arutha K shared an exciting world-first discovery! His team has profiled hundreds of proteins & thousands of gene messages from just a single tissue slide, using samples from 84 patients with head & neck cancer. bit.ly/4lyceNx

Now that we can assay thousands of plasma proteins in 1-2 ml of blood, there's discovery of many new cancer biomarkers nature.com/articles/s4155…

In Aug ’21, I was unwell, had 2 biopsies & waited weeks for answers. A liquid biopsy trial gave me an ALK+ #lungcancer diagnosis in 10 days. Now NHS England is rolling this out! 🎙️ Alastair Greystoke & I spoke w Roy Castle Lung Cancer Foundation on this & more: 👉 roycastle.org/our-support/po… #LCSM

scRNAseq cell type annotation is notoriously messy. Despite so many algorithms, most researchers still rely on manual annotations using marker genes In a new preprint accepted at ICML GenAI Bio Workshop, we ask if reasoning LLMs (DeepSeek-R1) can help with cell type annotation🧵

Very excited to share our preprint on #AI directed Deep Visual Proteomics (DVP) on #PancreaticCancer precursor lesions (PanINs), in collaboration with OmicVision Andreas Mund Thousands of proteins from as few as ~100 precisely microdissected cells in archival samples!

As a Latina diagnosed with #lungcancer in 2021, this hits home. So many of us don’t ‘fit the profile,’ yet we’re at risk. I love that the EQUAL study is focusing on Hispanic & Asian communities — Jill Feldman’s story is a powerful reminder that inclusion can save lives.

Backing brave thinking. Fuelled by collaboration.   A huge thank you to all the incredible researchers who joined us for our 2025 Researcher Symposium. Together, we’re not just imagining a future without cancer. We’re building it.   Read more here: curecancer.com.au/blog/celebrati…

Excited to share a milestone published in Nature Medicine from our decade-long effort to build The Human Phenotype Project, a unique longitudinal cohort with unmatched depth of clinical and multi-omic profiling, enabling truly predictive, personalized medicine. Led together with

Behind every biomarker is a person. It was an honor to co-author this comprehensive review on optimizing treatment for #EGFRm #NSCLC. acsjournals.onlinelibrary.wiley.com/doi/full/10.33… It isn't easy for a patient/advocate to contribute meaningfully to long, technical articles, but that's exactly why

What are "omics"? A good schematic cell.com/neuron/fulltex… could add epigenomics, immunomics, microbiomics, glycomics, exposomics, etc

Pathology-oriented multiplexing enables integrative disease mapping nature.com/articles/s4158… PathoPlex is a highly multiplexed imaging at subcellular resolution with a software package (spatiomic) to interpret protein co-expression patterns (clusters) across biological layers.

🛫 Arutha K presented at the World Immunotherapy Council (WIC) Asia-Pacific (APAC) Conference, in Singapore this week. A/Prof Kulasinghe shared his leading research on #multiomics and its role in precision medicine, particularly focusing on mechanisms of #resistance in #cancer.