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Late Breaking Science: IVIO, PARAMEDIC3 and VICTOR. The session unveiled results from two late-breaking clinical trials (IVIO and PARAMEDIC3) along with one published clinical trial (VICTOR) comparing initial intravenous (IV) versus intraosseous (IO) vascular access strategies

Here is the ILCOR evidence review and treatment recommendations for IV and IO access during resuscitation -now open for public comment costr.ilcor.org/document/io-v-… Australian Resuscitation Council ERC - European Resuscitation Council Resuscitation Council UK NZ Resus Council AHA CPR & First Aid TheResusRoom

New ILCOR CoSTR for the treatment of hyperkalemia Please comment “there is insufficient evidence to recommend for or against the use of calcium (weak-recommendation, very low certainty of evidence)” costr.ilcor.org/document/pharm… ILCOR Lars W Andersen Ari Moskowitz MD, MPH

Important letter by Lars W Andersen on limitations of observational studies Observational studies and causal questions in resuscitation research– ... sciencedirect.com/science/articl…

What causes acute kidney injury? Well, the list is long.... but IV contrast is not one of them. We reviewed 13 studies (9 retrospective, 4 prospective), which included 25,950 patients. Based on currently available data, CA-AKI is not a thing. Check out our review for more

The American Heart Association says not to give Sodium Bicarbonate during cardiac arrest, yet it is given in 50% of IHCA--WHY? Mike Donnino, MD Center for Resuscitation Science at BIDMC #OpenAccess sciencedirect.com/science/articl…

New meta-analysis of 3 RCTs: intraosseous and IV adrenaline yield similar 30d survival and neurological outcomes in 🫀arrest. Time to revisit current guidelines that recommends attempting IV before intraosseous access? Link: resuscitationjournal.com/article/S0300-… Resuscitation Asger Granfeldt

Thank you Keith Couper for leading the way on this important meta-analysis Intraosseous and intravenous vascular access during adult cardiac arrest: a systematic review and meta-analysis - Resuscitation resuscitationjournal.com/article/S0300-…

This was a tough one. 40000 abstracts screened. Limited evidence for the use of calcium for Hyperkalaemia Pharmacological Interventions for the Acute Treatment of Hyperkalaemia: A Systematic Review and Meta-analysis - Resuscitation resuscitationjournal.com/article/S0300-… Lars W Andersen

Should you use calcium to treat #hyperkalemia? 💉 Our new systematic review in Resuscitation (sciencedirect.com/science/articl…) found no evidence supporting calcium for hyperkalemia management. Thanks to Asger Granfeldt & Marie Jessen for inviting me to be part of this work! ILCOR

Academics are paid nothing for peer review. Yet journals made a total of over $8.3 billion on article processing charges alone between 2019-2023. Make it make sense.

RETWEET if you stand with President Zelensky!

Call for papers Innovations in Experimental Cardiac Arrest sciencedirect.com/special-issue/…

Hyperkalemia management: No supporting clinical effect was identified for calcium or bicarbonate. Is it time to rewrite all the order sets? 🎩 tip to the authors. eddyjoemd.com/foamed

🚨NEW: The Trump Administration has destroyed a mural of Dr. Anthony Fauci at the NIH Headquarters. The painting was there to honor his work to combat infectious diseases and inspire other health officials. RETWEET if you stand with Dr. Fauci against the Trump Administration!

The initiation of vasopressin following recommendations by a reinforcement learning model was associated with decreased mortality in patients with septic shock already receiving norepinephrine. ja.ma/4ksJYMF #ISICEM25

What happened here - 14 years between the abstract was published and the paper came out Beneficial Effect of Calcium Treatment for Hyperkalemia Is Not Due to "Membrane Stabilization" Crit Care Med 2024 Vol. 52 Issue 10 Pages 1499-1508 doi.org/10.1016/j.anne…

Superb summary of Danish IVIO trial- Asger Granfeldt Lars W Andersen I guess it would have been a much firmer "IV please" if based on UK Paramedic-3 trial nejm.org/doi/full/10.10…

Great work by Peter Carøe Lind - even small changes in potassium is associated with increased risk of in-hospital cardiac arrest Potassium Levels and In-Hospital Cardiac Arrest: A Matched... : Critical Care Medicine journals.lww.com/ccmjournal/abs…

Proud of this editorial on proning in VV-ECMO patients link.springer.com/article/10.100… rdcu.be/emLo7