
Asim Khan
@asim_g_khan
Columbia PhD Student | Former Shipman Lab | UCLA Alum | Sports Analytics @KF_soccerPicks
ID: 1344349617484304385
30-12-2020 18:28:33
91 Tweet
39 Followers
155 Following








An experimental census of retrons, now published in Nature Biotechnology. We synthesized more than a hundred new retrons and put them through their paces, improved recombineering rates and precise editing in human cells up to 40%. nature.com/articles/s4158âŚ

Here's the SharedIt link for free access to the paper: rdcu.be/dUbL7. Great job on this one Asim Khan MatĂas Rojas Montero Alex GonzĂĄlez-Delgado oso Rebecca Fang kate crawford, and institutional support Gladstone Institutes UC San Francisco UCSF Bioengineering & Therapeutic Sciences

Gladstone scientists undertake a major effort to examine the diversity of retrons, bacterial defense systems that can be leveraged for precise gene editing. Seth Shipman Asim Khan MatĂas Rojas Montero Alex GonzĂĄlez-Delgado Nature Biotechnology UC San Francisco UCSF Bioengineering & Therapeutic Sciences Chan Zuckerberg Biohub Network bit.ly/3XIMoxb

đ¨ NEW PUBLICATION đ¨ "An experimental census of retrons for DNA production and genome editing" Seth Shipman Asim Khan MatĂas Rojas Montero Alex GonzĂĄlez-Delgado Nature Biotechnology UC San Francisco UCSF Bioengineering & Therapeutic Sciences Chan Zuckerberg Biohub Network nature.com/articles/s4158âŚ

đ¨New Pub: High throughput variant libraries and machine learning yield design rules for retron gene editors, now out in Nucleic Acids Res. This is a great one, and the last bit of kate crawford's PhD, who is off to David Bakar's Lab for a postdoc. academic.oup.com/nar/advance-arâŚ


The sequel to our DRT2 story is here, and this one is once again full of surprises! This time around, the Sternberg Lab teamed up with the Wiedenheft Lab to study how DRT9 reverse transcriptases provide antiviral immunity. Hereâs what we found: biorxiv.org/content/10.110âŚ



Thrilled to see our work on the cover of Nature Biotechnology

New Preprint!! Alex GonzĂĄlez-Delgado accomplished a major feat on this one: ported retron recombineering, which we love so much in E. coli, into 14 new bacterial species via a massive collaborative effort involving 9 labs! biorxiv.org/content/10.110âŚ