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#ENEA2024 VALIDATION OF BASELINE LABORATORY LEVELS AND A NOVEL PROBABILITY SCORE IN THE DIAGNOSIS OF PATIENTS WITH SUSPECTED ARGININE VASOPRESSIN DEFICIENCY Cihan Atila Clinical Neuroendocrinology Basel 🆕 algoritmo!! ENEA EYRC Aqua - SEEN NeuroendocrinoSEEN

Join us at the EYRC symposium at the #ENEA2024 meeting 🇪🇸! Cihan Atila is starting the session!

Oxytocin deficiency – does it exist, how to test for it, and is there any treatment available? Cihan Atila #ENEA2024 ENEA EYRC European Society of Endocrinology (ESE) NeuroendocrinoSEEN

What an incredible ENEA 2024 Congress 🎉 A massive thank you to all participants, speakers, and organizers for making this event a huge success! 🙌Your contributions have been invaluable, and together, we’re pushing the boundaries of neuroendocrine research. Until next time! 💪

🎉 Thrilled to announce I received the Best Oral Presentation Award at ENEA 2024 in Sevilla! 🙌 It was an honor to present my work on vasopressin and to lead a symposium on oxytocin.   A huge thank you to the incredible community for this recognition!  EYRC ENEA

🚨 Exciting news from the EYRC! 🚨 Introducing #NeuroendocrinologyWatch 🧠🔬— every two weeks, we’ll spotlight cutting-edge research in neuroendocrinology. Stay tuned for the latest breakthroughs, insights, and must-read papers! 📄✨ First feature coming soon! 👀 ENEA

🚨 Neuroendocrinology Watch spotlighting Mamelak et al. in JCEM. 1️⃣Surgery for severe cases, but med & surgic. outcomes similar in 100 apoplexy cases 2️⃣Timing of surgery didn’t affect outcomes—expert neurosurgeon transfer is key 3️⃣Med mgmt reduced tumor volume at 3 months

I am very proud to have worked on this review just published in The Lancet Diabetes & Endocrinology on Aberrant hormone receptors & Endocrine tumors The Lancet Diabetes & Endocrinology thelancet.com/journals/landi…

🎉Huge congratulations to the #EYRC award winners at #ENEA2024! 🏅 Oral Basic: Athina Mavropoulou 🏅 Oral Clinical: Cihan Atila 🏅 Poster Basic Research: Federica Mangili 🏅 Poster Clinical: Loren Van der Hoeven Your outstanding work is shaping the future of ENEA

🚨 Neuroendocrinology Watch spotlighting Piña et al. 1⃣ Gene expression annotations align with pathologists' findings. 2⃣Notable intratumor heterogeneity observed in cell clusters. 3⃣Spatial transcriptomics shows promise for small pituitary tumors without multiple stains.

🚨 Neuroendocrinology Watch highlighting the paper by Lin et al in Genome Medicine. 🧠 Key insights: 1️⃣ Single-cell transcriptomics of 23 PitNETs. 2️⃣ Discovery of 5 potential macrophage subtypes. 3️⃣ CX3CR1+ macrophages may induce tumor apoptosis via the INHBA-ACVR1B axis.

🔆Neuroendocrinology Watch🔆 New insights on papillary CP treated with BRAF/MEK inh. by Alcubierre et al: 🔹 94% response, with improved headaches, vision & neuro symptoms. 🔹 Tumor volume reduction: 89% (neoadj.), 73% (adj.), 92% (pallia.). 🔹 63% tolerated treatment well

“Exogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement” has been selected as the Endocrine Reviews Featured Article this week doi.org/10.1210/endrev… Many thanks to my co-authors! Endocrine Society European Society of Endocrinology (ESE) Metabolism and Systems Science (MSS) Birmingham Health Partners University Hospitals Birmingham

🔆 Neuroendocrinology Watch 🔆 highlithing Lin B et al., Adv Sci 2024, reveal microbiome-metabolome links in craniopharyngioma. - ↑ Clostridium & disrupted purine metabolism - Hypoxanthine ↔ hypothalamic comorbidities - Redox imbalance fuels CP progression

🔆 Neuroendocrinology Watch 🔆 “Phenotype of Pediatric Cushing Syndrome without Obesity” Padilla C et al., EJE, 2024 • Non-obese patients: older, mostly female, advanced puberty. • Different BP profiles by obesity status. • Weight gain not the only clue—screen for hypercort.

🚀 Excited to Launch “EYRC Interview - Career in Progress,” where we spotlight mid-career researchers shaping the field of neuroendocrinology 🌟 First up: Dr. Nicole Bechmann, a leader in adrenal gland tumor research! Link to the full interview: youtube.com/watch?v=QsCaM5…

💡 Does arginine stimulate vasopressin via urea? ✅ Urea increased after arginine. ✅ Copeptin increased in healthy adults & primary polydipsia, but not in AVP deficiency. ❌ Urea & copeptin correlation? Weak. 📖 Read more in Pituitary: rdcu.be/d7wNs

Neuroendo Watch: AI-assisted surgical decision-making tool by Bou-Nassif et al. ✅ AI-powered tool analyzes millimetric tissue fragments intraoperatively ✅ Differentiates normal pituitary vs. adenoma with high accuracy ✅ Useful in centers without a neuropathologist

🚀 Exciting News! The EYRC Podcast is LIVE! The EYRC is launching a brand-new podcast covering the latest expert interviews! 📌 EYRC Podcast Hub: enea.org/category/eyrc-… 🍏 Apple Podcasts: podcasts.apple.com/fr/podcast/ene…

🚀 Neuroendo Watch We highlight a study in Endocrine with new insights into MEN5 📌 First reported case of pituitary gigantism linked to a germline MAX mutation 📌 Identification of myelolipoma as a new disease association  📌 Expansion of the MEN5 phenotype beyond  (PPGLs)