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BBC News: IBS trial to test amitriptyline as potential common treatment bbc.co.uk/news/uk-englan… atlantis_trial Amy Herbert CAPC, Bristol Alexander Ford @HazelEveritt @crnwestengland

atlantis_trial has just randomised the 450th person with #IBS to amitriptyline or placebo. Great work team! 🌊🌊🌊

We now have 450 participants taking part in the study!! 🎉🎉 Such a huge achievement! Thank you so much to all involved! 💙🤩 #ThankYou #GoTeamAtlantis #BePartofResearch #IBS @crnwestengland @NIHRCRNWessex NIHR CRN Yorkshire & Humber

Our team have randomised 43 patients into the trial throughout March alone!! Thank you so much to our AMAZING Research team and GP sites for all your hard work and efforts! 🙏 #YouAreAmazing #ThankYou #GoTeamAtlantis @crnwestengland @NIHRCRNWessex NIHR CRN Yorkshire & Humber

It's a wrap! atlantis_trial has recruited its last patient. In all, 463 patients were randomised to amitriptyline or placebo. A massive well done and thank you to all the team, the GP surgeries, and the participants. We couldn't have done it without you! National Institute for Health and Care Research 🌊🌊🌊

Recruitment on the trial has come to an end today with an amazing total of 463 participants randomised into the study.🤩 Big well done to the team and thanks to all who are taking part!! 👏💙 #GoTeamAtlantis🌊 #WellDone #Thankyou @crnwestengland NIHR CRN Yorkshire & Humber @NIHRCRNWessex

Fantastic effort from an amazing team atlantis_trial 👏🥳🍾 463 people with #IBS recruited in #PrimaryCare to this commisioned National Institute for Health and Care Research #RCT 👀 Full results due 2023 @LeedsMedHealth Leeds CTRU CTRU Complex Interventions

Team ATLANTIS are proud to be raising awareness for #WorldIBSDay yesterday. #HereForYou💙

(1/3) Despite the challenges of the pandemic, some of our trials were still able to recruit well. atlantis_trial completed recruitment in April with over 460 patients with IBS recruited from primary care, making it the largest ever trial of amitriptyline for IBS! #ICTD2022

(2/3) For ATLANTIS, the role that Research Nurses played in recruitment was a crucial factor, with dedicated trial research nurses assessing eligibility, recruiting patients, and conducting trial follow ups over the phone #ICTD2022

(3/3) Support was also received from CRN Research Nurses and Research Nurses at some participating GP sites #TrialRecruitment #ICTD2022

Happy #InternationalClinicalTrialsDay 😃

#ThankYou to all our wonderful participants for taking the time to complete the study questionnaires. Please continue to do so - your follow up information is really important to us🙏 #BePartofResearch #IBS #IBSTrial

atlantis_trial Amitriptyline at low-dose and titrated for irritable bowel syndrome as second-line treatment (ATLANTIS trial): protocol Sarah Alderson Alexander Ford @HazelEveritt Prof Amanda Farrin 🕷️🇪🇺 💙

Our atlantis_trial protocol is now published! Amitriptyline or placebo for 2nd line irritable bowel syndrome: trialsjournal.biomedcentral.com/articles/10.11…

Protocol paper out now for our atlantis_trial in #PrimaryCare - final results due in 2023 👀 Leeds CTRU CTRU Complex Interventions @LeedsMedHealth Alexander Ford

Delighted to announce that the atlantis_trial of low-dose titrated amitriptyline as a second-line treatment for #IBS in primary care is now published online in The Lancet authors.elsevier.com/sd/article/S01… I will be presenting the results today at 1430hrs at #UEGWeek2023

We will be running an ATLANTIS webinar for patients who have IBS on 30th January 2024 at 5.30 – 7pm to discuss the results of the ATLANTIS study and we will provide the opportunity for you to ask questions. If you are interested in attending, please visit ctru.leeds.ac.uk/atlantis/

Register now - trybooking.com/uk/CULN to join the ATLANTIS webinar on Tuesday 30 January 2024 at 5.30 - 7.00pm to hear about the results of the ATLANTIS trial. The webinar will be held by zoom and joining details will be sent to those who register via the link above.