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Analyzing organelles is HARD. They're complex, but critical to understanding biology. Current tools are manual, organelle-specific, or can't handle large 3D datasets. With an easy install and a click of a button, Nellie solves ALL these problems! nature.com/articles/s4159… 🧵2/N

New from Lefebvre and colleagues! Nellie is a comprehensive automated pipeline for studying the structure and intracellular dynamics of diverse organelles that offers accurate segmentation, tracking and feature extraction on both 2D and 3D data. nature.com/articles/s4159…

In the physical world, almost all information is transmitted through traveling waves -- why should it be any different in your neural network? Super excited to share recent work with the brilliant Mozes Jacobs: "Traveling Waves Integrate Spatial Information Through Time" 1/14

Already some cool applications for Nellie: If you're used to MitoGraph data and want some of the same outputs from Nellie, check out Gav's Python code.

Even mis-segregations are aesthetically pleasing

I’m hiring for a microscopy image analysis role at Calico! calicolabs.com/careers/?gh_ji… We’re looking for someone at ~recent PhD lvl who has previous experience with biological samples and analyzing microscopy datasets. Feel free to reach out with any questions!

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15