
Aviv Spinner
@avivspinner
Protein Eng ML Research Fellow @Align_Bio
Previously PhD w/ @deboramarks, ML Researcher @Flagship_PI, investor @pillar_vc & scientist @scribetx. 🧬🧑💻 🏳️⚧️
ID: 606017509
12-06-2012 04:34:53
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877 Followers
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Congrats to Alyssa Morrow and others on this latest work: a model for designing full-length mRNA sequences for a given protein sequence 🧬


I am reviewing papers for GEMBio Workshop this morning and genuinely having such a good time -- y'all get ready for a wild set of papers to drop soon!! quality is honestly through the roof this year! 📈🐂

What's better than 1 deep mutational scanning (DMS) library? 2! In a new pre-print Brittney Thornton and Rachel F Weissman et al. map the mutational landscape of ISDra2 TnpB protein and reRNA and leverage these datasets to engineer highly active variants (1/9)


🚀 New proposal from Align! The experimental platform aims to standardize #microbial #phenotyping & support predictive modeling. :🦠 Capturing data across 1k strains & 1k conditions; using BacterAI; generating high-quality datasets for ML Jensen Lab buff.ly/3rO55fA




In @nature we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR-Cas9 enzymes, offering safer & more genome editing tools. 🧬🖥️ Rachel Silverstein CGM at MGH @MGH_RI MassGeneral News Harvard Medical School nature.com/articles/s4158…

Machine Learning Engineers Bespoke Cas9 Enzymes for Gene Editing Read more of what Ben Kleinstiver and Rachel Silverstein from HMS had to say in an interview with GEN's Fay Lin, PhD. MassGeneral News Harvard Medical School hubs.li/Q03jt42N0








is Protriever the end of MSAs??? excited about this Ruben Weitzman @ ICLR 2025 also, Pascal Notin has a phenomenal substack that I can't recommend enough. He goes through this paper and does a deeeeeep dive on the rationale! pascalnotin.substack.com