We present Compression #Microscopy (CoMic) as a new #superres modality. By compressing the sample it is made inaccessible by conventional imaging, thus necessitating superres. CoMic allow imaging of macro-structures by superres, and could make diffraction-limited imaging obsolete

Exciting news! We're looking for a talented Ph.D. candidate to join our group as a synthetic chemist. If you're passionate about developing tech that let us re-examine the big questions in neuroscience, we want to hear from you! SciLifeLab @UU_University uu.se/en/about-uu/jo…

RIBOmap for spatially resolved single-cell translatomics is published today! Congrats to the whole team and thanks so much for the constructive feedback and great suggestion from the editor, reviewers, colleagues, and friends! science.org/doi/10.1126/sc…

Back to the brain and microscopes. Pretty thankful this #FluorescenceFriday

Excited to share our new method for label-free imaging of DNA origami nanodevices in Nature Nanotechnology. We hope origamiFISH will be a resource to the community, and help in future expansions of the DNA nanotech toolbox. Leo Chou Travis Douglas Meghan nature.com/articles/s4156…

Say hello to a new class of Damon Runyon Fellows! We’re honored to announce these thirteen remarkable postdoctoral scientists who are joining our #braveandbold mission to advance cancer research. Learn more about our new Fellows: bit.ly/3OGHCKL

📢 Here's our next #NanoBio journal club meeting for Sept! 🗓️ Thurs Sept 28, 4:30pm US Eastern / 1:30pm US Pacific 🗣️ Wendy Wang, PhD (Wendy Xueyi Wang, prev. Leo Chou lab, Biomedical Engineering @ University of Toronto ) 📑 nature.com/articles/s4156… 🛰️ tinyurl.com/NanoJCSept2023 Open to everyone, register above ☝️🏻☝️🏻☝️🏻

Thrilled to see our work finally online! We utilized in situ spatial transcriptomic method STARmap PLUS to map 1.09 million cells in the adult mouse central nervous system at molecular resolution and identified previously unknown tissue architectures. nature.com/articles/s4158…

Excited to share our manuscript on bioRxiv where we adapted origamiFISH (DNA origami detection in cells and tissues via fluorescent in situ hybridization, FISH) from confocal imaging to flow cytometry, origamiFISH-Flow! doi.org/10.1101/2023.1…

Hey #SfN2023! Mark SOC02 on your meeting planner for the Bridging the Synapse Social, on Sunday 6:45-8:45 pm. Co-hosted by WilliamsLabUtah and I. We will have icebreakers and stimulating interactions. Please RETWEET/Repost!

A new approach to visualize 🧬 #DNAorigami within living cells by Leo Chou lab! 🧫🔬✨It was a great pleasure to write this #Newsandviews for Nature Nanotechnology ! Free access using this link! 👇🏿👇🏽👇🏿👇🏻 nature.com/articles/s4156…

Why did we make EzReverse? When a color image is inverted in RGB colorspace, the colors are changed and this is usually not what you want:

Congratulations to Xiao Wang (Xiao Wang), the Cabot Assistant Professor of Chemistry and a Core Member of Broad Institute , who has been promoted to Associate Professor With Tenure, effective July 1, 2024. chemistry.mit.edu/chemistry-news…

Oxford nanopore sequencing

Check out our lab's new work by the talented Xin Sui (two first author papers in one day!). He integrates new methods for probe synthesis and polymer chemistry for cheap, scalable profiling of the transcriptome and translatome in intact tissue blocks. +1 for morphology

Get lost in twin neuronal universes! 😍 💫 These images taken by @FelipeCourtg with a fluorescence microscope shows neuron-glia crosstalk, which is a key phenomenon for understanding brain diseases like Alzheimer's and Parkinson's

CAST enables physical alignment of spatial omics data across replicates, techs, modalities at single-cell resolution. Such accurate alignment enables spatial atlas searching, unbiased DEG identification, and reconstruction of spatial multi-omics. DM for questions and collabs!

Synthesizing RNA can be as fun as LEGO puzzles! This work is co-led by my incredible colleagues Dangliang Liu and Abhi Aditham . Huge thanks to my supervisor Xiao Wang for such amazing ideas. We are also grateful for the editor, reviewers, and all collaborators along the way.

Check out Alexander Nectow cool new study on the role of CCK neurons in the DRN for regulating satiation, out today Cell ! Excited to have contributed to this work.

A hidden constellation. #FluorescenceFriday