Happy to share our work just out at JITC! We highlight the potential of targeting EZH2 as a therapeutic strategy to enhance MHC-II expression and improve immunotherapy efficacy. Jamaal L. James BalkoResearchLab

Let’s take a closer look at “Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance” by Brandie Taylor BalkoResearchLab at @VUBasicScience Vanderbilt University Medical Center 1/9

Congrats Brandie Taylor!!! Susan G. Komen ASPIRE superstar! So proud

Excited to announce our new publication in Scientific Reports examining the role of talin-1 in macrophages during infectious colitis. Special thanks to our collaborators in the Jeremy Goettel lab! We did it Yvonne Latour !!🍾🥳 pubmed.ncbi.nlm.nih.gov/38102166/

A recent paper from the @balkolab, led by Jamaal James and @bct255, indicates that EZH2 inhibition leads to enhanced MHC-II expression potentially through the improvement of chromatin accessibility at CIITA, the master regulator of MHC-II. doi.org/10.1136/jitc-2…

Join us in two weeks as Emily Hawes (Emily Hawes), a graduate student in the lab of Richard O'Brien, presents her dissertation work on the "Regulation of Glucose-6-Phosphatase Catalytic Subunit 2 (G6PC2) Expression and Activity!"

From the February issue— #NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by Brandie Taylor, Xiaopeng, BalkoResearchLab et al. bit.ly/49CFb4U Vanderbilt University Medical Center #TNBC

Save the date for Vanderbilt Cancer Biology Graduate Program Melissa M Wolf's (Kimryn Rathmell & Jeff Rathmell labs) dissertation defense! “VHL Deficiency and the Tumor Microenvironment in Renal Cell Carcinoma” Friday, March 1st 3:30 PM PRB 898J

Join us TODAY! Ela W. Contreras Panta , Goldenring Lab, Vanderbilt Cell and Developmental Biology, Vanderbilt School of Medicine Basic Sciences

Today is the AACR Early-Career National Day of Action, and we're calling on early-career scientists, trainees, students, and all who support them to contact members of Congress and ask them to prioritize NIH funding. Take action: AACR.org/AACRECHD24 #AACRontheHill #FundNIH

Representing Tennessee by spending a day on the Hill to support NIH funding! Grateful to have met with TN Senators Sen. Marsha Blackburn and Bill Hagerty. AACR #AACRonthehill #FundNIH

We had a very productive 9th Annual Early-Career Hill Day. Our 20 AACR Associate Members are wrapping up their meetings, but you can still take action in support of early-career scientists by visiting bit.ly/48yoSoV. #AACRontheHill #FundNIH

Congratulations to Cancer Bio student Ebony Hargrove-Wiley & Meharry-Vanderbilt Alliance students Sydney Jamison and Claude Albritton for securing participation in Endocrine Society's #FLARE2024 program! medschool.vanderbilt.edu/basic-sciences… Antentor Othrell Hinton, Jr PhD (A.J. Hinton) Annet Kirabo D.V.M., M.Sc., Ph.D., F.A.H.A. Barbara Fingleton Vanderbilt Molecular Physiology & Biophysics Vanderbilt Pharmacology

I am defending my dissertation next week on March 15th! Grateful for the mentorship by BalkoResearchLab ! DM me if you would like the zoom link.

I'm defending next week on March 21st at 11:30 am central time. Stop by to hear about the secrets of CFTR revealed.. DM me for a zoom link Plate Lab and Jens Meiler Lab

Today at 2pm in LH214!

So proud of this outstanding scientist and person Brandie Taylor defending her thesis today. A Susan G. Komen ASPIRE scholar, Cancer Discovery Journal for ImmunoTherapy of Cancer published author and all around superstar. Can't wait to see what the future holds!! @VUMCResearch Vanderbilt School of Medicine Basic Sciences

Komen grantee BalkoResearchLab presents his work on understanding and improving #breastcancer response to immunotherapy @ #AACR24. To learn more, check out the MBC Impact Series where he discussed his work: bit.ly/4cFtpsN

Excited to announce that I will be defending my dissertation with the work from Rafat Lab and Rhoades Research Lab! If you are interested in attending, please let me know!

Please join us in supporting Menghan Mei of the Ren lab as he defends his thesis tomorrow (Thursday, 8/22)!