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Interesting piece. 2 of 3 scientists mentioned, Muotri & Hanna, are among the most controversial in the area. (Matt Porteus, the 3rd, isn't.) Surprised it didn't mention the NASEM report on this topic, issued in April 2021. Also surprised I hadn't heard about the meeting.

Great article about the ethical challenge of human brain organogenesis in a dish.

Debunking another bullshit paper on Neanderthals coauthored by a newly minted The Nobel Prize winner. Comment on “Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals” science.org/doi/10.1126/sc…

Important new review on "embodied mind". Buzsáki and Tingley: cognition from allostasis. annualreviews.org/doi/abs/10.114…

Too delicate a topic? This very well written and most comprehensive take on human brain organoid ethics was rejected by many journals! Congrats to Meagan and team for persisting! Pitt Neurosurgery BrainOrganoid UPMC Hillman Cancer Center @AHabibMD

Excellent work by F.Ridvan Kiral, Bilal Cakir, Yangfei Xiang, and Yoshiaki Tanaka lab@UdeM is finally out at Cell Stem Cell to generate ventrally fated human thalamic organoids. cell.com/cell-stem-cell…

Why do we still have journals when we can publish our work on the internet, open access, with post publication review and discussion?

In a new theory of embodied consciousness, neuroscientists Antonio Damasio & Hanna Damasio propose that feelings are the source of consciousness. W/o them, consciousness is impossible–w/radical implications for the ‘hard problem’ of consciousness & ... AI iai.tv/articles/consc…

Philipp Wörsdörfer (@woephi) and colleagues describe a novel neuro-#mesodermal #assembloid model that recapitulates aspects of peripheral nervous system development, such as #NeuralCrest cell induction, and much more! 📖 Full study in StemCellReports: bit.ly/43LJ6u2

70 years ago, 3 papers appeared in nature under the title ‘Molecular structure of nucleic acids’. In an article in Nature today (link at end) Nathaniel Comfort and I shed new light on ‘what Watson and Crick really took from Rosalind Franklin’. This thread summarises our findings. 1/23

Most likely…

🚨New Research Topic🚨 We are excited to announce a new Research Topic on Developmental Brain Diseases Through the Lens of iPS Cells and Organoids Led by Drs. Gabriel G Haddad, Alysson Renato Muotri and Fred H Gage ➡️ Learn more here: fro.ntiers.in/sMHZ

A new preprint suggests postmortem brains are a poor stand-in for living brains in studies of neurological conditions, including autism, though several scientists disagree. spectrumnews.org/news/preprint-…

Plus, it’ll also provide information about what will happen to our brains if we all decide to migrate to Mars! Thanks Dr Alysson Muotri & UC San Diego ! the-scientist.com/scientist-to-w…

Truly amazing, pushing the boundaries with out-of-this world research.

Very interesting #PAX6 cerebral #organoid work by Wai Kit (Calvin) Chan John Mason and colleagues, uncovering phenotypic properties not previously observed based on mouse models 🧫🧠🧬: biorxiv.org/content/10.110…

The The Knoblich Lab and the Treutlein lab show that perturbation of 36 high-risk #autism spectrum disorder genes 🧬related to transcriptional regulation uncovers their effects on cell fate determination. 🎉 Congratulations to the team on their study! go.nature.com/488AuA5

The projecting axons of neurons (red) from a human brain organoid grow out across a culture dish. Their nuclei are stained blue. Credits: Alysson Muotri #MedTwitter