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"The bidirectional relationship between metabolism and cell cycle control" sciencedirect.com/science/articl…

What do leaders in their fields think about the present and future of #organoids? Read key insights and watch presentations by Drs. Hans Clevers, Madeline Lancaster, Meritxell Huch, and more from this “Advances in Organoid Applications” Round Table. bit.ly/3aqSN5T

Our latest📰! Out today in Molecular Cell We used single-molecule imaging to directly observe human BRCA2 tumour suppressor in action! Spearheaded by Ondrej Belan & Luke Greenhough. A thread. (1/10) sciencedirect.com/science/articl…

Introducing DROPPS! Here's our preprint that describes an accesible approach to low input proteomics and how we applied it to generate some interesting biological insights (1/x) biorxiv.org/content/10.110…

An awesome day for the Terry Fox run, and so many families out with kids. MOMICs team folks ran at YYZ & YVR

1 in 8 Canadian women will be diagnosed with breast cancer. During the month of October, we need your help to generate awareness and raise funds for life-saving breast cancer research. To register for or donate to the Raise More Challenge, please visit knowmoreraisemore.ca.

Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages dlvr.it/SxxjW6

Excited to share our work “Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice“. Led by Lauren Podmore and Yekaterina Poloz, our study reveals a major function of INSR in breast/mammary tumour initiation, likely independent of its kinase activity.cell.com/cell-reports/f…

NEW content online! Metabolic pathway analysis using stable isotopes in patients with cancer dlvr.it/SyC8l6

Please check out Curtis McCloskey’s amazing work creatively leveraging scRNA-seq to discover and characterize a novel mammary progenitor population with implications for high-risk BRCA1 mutation carriers! Delighted and grateful for the opportunity to be a part of this project! 🙌

The Career Development Association Medical Biophysics would like to invite alumni/early career professionals for seminars to share their career journeys! #uoft #uhn #careertalks

Happy to share the first preprint from the lab! Led by Sharon and made possible by the contributions of Prashant Nuthalapati Jacqulene Subhajit Maity Dun Ning, Grant Shryock, Zhenyu Xuan UT Dallas Biology UTD Natural Sciences & Math and AACR funding😊

Metabolic regulation of the hallmarks of stem cell biology dlvr.it/T2BVsm

Checkout our new paper, describing a simple method to analyze low amounts of flow sorted cells by Matt Waas and team Droplet-based proteomics reveals CD36 as a marker for progenitors in mammary basal epithelium: Cell Reports Methods cell.com/cell-reports-m…

Really pleased to share our new in vitro model of the normal mammary gland. link.springer.com/article/10.100… Thanks to all the authors, to the ladies who donated tissue through @MCRCBiobank and to Prevent Breast Cancer for funding the work. Manchester Breast Centre

UPDATE: The Canadian Cancer Society is updating its position on breast screening to reflect evolving evidence and calls for action from patients who are frustrated that many women aged 40 to 49 are being excluded from breast screening as well as the national guidelines developed

A small part of the group who made it out this morning to the #TFRI10SM Terry Fox Run! As always, Terry guided the way! Terry Fox Research Institute Marathon of Hope Cancer Centres Network Terry Fox Foundation

RESEARCH | Y Qiu, M Lukey et al. (@CHSL): The study provides insight into the metabolic adaptations that enable breast cancer cells to proliferate in the face of glutaminolysis blockade. #CancerResearch nature.com/articles/s4225…

Happy to share my first PhD paper from @PLynneHowell lab with my fantastic post-doc mentor Greg Whitfield from Brun Lab as well as Lori L. Burrows and @RubinsteinJohn with #cryoem support where we propose how the bifunctional Tad pilus motor works🧵 biorxiv.org/content/10.110…

Can metalloproteinase inhibitors advance strategies for repopulating damaged tissues? Rama Khokha & team University Health Network discover natural protease inhibitors regulate the liver progenitor niche via sDLK1: jci.org/articles/view/… Princess Margaret Cancer Centre Research Ontario Institute for Cancer Research (OICR) CIHR-ICR | IC-IRSC Research at Canadian Cancer Society