First in person meeting to discuss our CaixaResearch project on #PancreaticCancer cell of origin! 😃👩🏻‍🔬 Great discussion and amazing energy to move things forward! 💪🏻 Rovira_lab Psancholab @BiocomicsLab

Had a truly inspiring experience at the @BottonChampalimaud #PancreaticCancer Conference - reconnected with friends and colleagues, to advance pancreatic cancer research and patient care. Anirban Maitra Ben Stanger Saur Lab and many more... Reichert Lab

Which are the highest cited original research publications in #PancreaticCancer over the past five years (from 2020 to 2024 end)? All metrics obtained from Google Scholar (caveat: GS tends to OVERESTIMATE citations but the trends are consistent overall). 🧵 Below:

🚨New paper alert: Intratumoral co-existence of PDAC subtypes -- what's the environmental drivers and underlying mechanisms? A fantastic collaboration with Shiv K Singh & Lab's team, just out in Nature Communications !👨‍🔬

It took 3 years, 4 rounds of reviews, 96 VISIUM samples, 10 cancer types, and 1 clinical trial, but it's finally out: The spatial landscape of Cancer Hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity Here's what's new 👇 cell.com/cell-reports/f…

Evolutionary fingerprints of epithelial-to-mesenchymal transition | ⁦nature⁩ nature.com/articles/s4158…

linkedin.com/posts/lena-h%C…

Funny how two of the more interesting pieces of data at #ASCO25 have little to do with extraneous medications per se, but rather the body’s circadian rhythm and physiology: 1: Exercise after surgery 2: Checkpoint inhibitors in the morning

New cross species study examining #PancreaticCancer precursors in Journal of Clinical Investigation from Dr. Neeha Zaidi Won Jin Ho Dr. Elizabeth Jaffee Johns Hopkins Kimmel Cancer Center Spatial Proteomics and Transcriptomics Reveal Early Immune Cell Organization in Pancreatic Intraepithelial Neoplasia insight.jci.org/articles/view/…

First day EPC-Europ Pancr Club 57th meeting in Düsseldorf epc2025.eu 🤯🤯🤯 Joint post-graduate course with European Society of Pathology (ESP): Great start with excellent pathology talk by Volkan Adsay 👏🥇💥💥💥

Final COMPASS trial data advanced #PDAC ➡️268 WGS& 253RNA-seq ➡️basal-like& hi GRIm-S ⬇️OS, both unique TME inc CD8 variation,NB primaries vs mets ➡️LTS :HRD, KRAS WT ➡️KRAS major enriches basal, >type II DM ➡️LAPC≠intact SMAD4 ➡️47% receive 2nd line tx nature.com/articles/s4146…

Proud to share Jose M. Adrover’s (new PI The Francis Crick Institute) paper: As a postdoc (Cold Spring Harbor Laboratory/Johns Hopkins Medicine), he found #NETs in necrotic tumors—I shrugged. But he looked closer: NETs block tumor vessel perfusion, causing necrosis, hypoxia, EMT & #Metastasis. nature.com/articles/s4158… @JHU_BDP nature

Terrific preprint by Hartland Jackson using imaging mass cytometry (IMC) & matched genomics for building multimodality prediction models: Integrated spatial proteomics of human PDAC uncovers an expanded tumour–immune– stroma spectrum with genomic associations biorxiv.org/content/10.110…

The New York Munich Goettingen crew has landed in Lisbon for Peter Bailey #PancreaticCancer research meeting! Saur Lab Maximilian Reichert Chiara Falcomatà Barbara Grünwald